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New antimicrobial anthraquinone 6, 61-bis (1, 5, 7- trihydroxy-3 hydroxymethylanthraquinone) isolated from Streptomyces sp. isolate ERI-26
Joint Authors
al-Dhahabi, Nayif Abd Allah
Ignacimuthu, S.
Duraipandiyan, V.
Source
Saudi Journal of Biological Sciences
Issue
Vol. 23, Issue 6 (30 Nov. 2016), pp.731-735, 5 p.
Publisher
Publication Date
2016-11-30
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Pharmacy, Health & Medical Sciences
Medicine
Abstract EN
The present report is about Streptomyces sp.
isolate ERI-26 isolated from the soil sample of Nilgiri forest, Western Ghats.
The methanol extract of ERI-26 showed good antimicrobial activity against tested microbes.
The antimicrobial novel anthraquinones were purified by bioactivity-guided fractionation using a silica gel column and preparative HPLC.
The compound was characterized and identified by UV, IR, NMR and MASS spectral data.
The compound named as 6,61-bis (1,5,7-trihydroxy-3-hydroxymethylanthraquinone), showed significant antimicrobial activities against tested microbes.
The isolated compound inhibited the tested bacterial growth, Staphylococcus aureus at 62.5 lg/ml, Staphylococcus epidermidis at 15.62 lg/m, Bacillus subtilis at 62.5 lg/ml, fungi; Trichophyton mentagrophytes at 15.62 lg/m Trichophyton simii at 15.62 lg/ml, Aspergillus niger at.
7.81 lg/ml, Aspergiller flavus at 3.90 lg/ml, Trichophyton rubrum 296 at 62.5 lg/ml, T.
rubrum 57/01 at 7.81 lg/ml, Magnaporthe grisea at 15.62 lg/ml.
and Botrytis cinerea at 3.90 lg/ml.
Isolated anthraquinone compound and its antimicrobial activity were newly reported.
_ 2016 The Authors.
Production and hosting by Elsevier B.V.
on behalf of King Saud University.
This is an open access article under theCCBY-NC-NDlicense (http://creativecommons.org/licenses/by-nc-nd/4.0/).
American Psychological Association (APA)
Duraipandiyan, V.& al-Dhahabi, Nayif Abd Allah& Ignacimuthu, S.. 2016. New antimicrobial anthraquinone 6, 61-bis (1, 5, 7- trihydroxy-3 hydroxymethylanthraquinone) isolated from Streptomyces sp. isolate ERI-26. Saudi Journal of Biological Sciences،Vol. 23, no. 6, pp.731-735.
https://search.emarefa.net/detail/BIM-717178
Modern Language Association (MLA)
Duraipandiyan, V.…[et al.]. New antimicrobial anthraquinone 6, 61-bis (1, 5, 7- trihydroxy-3 hydroxymethylanthraquinone) isolated from Streptomyces sp. isolate ERI-26. Saudi Journal of Biological Sciences Vol. 23, no. 6 (Nov. 2016), pp.731-735.
https://search.emarefa.net/detail/BIM-717178
American Medical Association (AMA)
Duraipandiyan, V.& al-Dhahabi, Nayif Abd Allah& Ignacimuthu, S.. New antimicrobial anthraquinone 6, 61-bis (1, 5, 7- trihydroxy-3 hydroxymethylanthraquinone) isolated from Streptomyces sp. isolate ERI-26. Saudi Journal of Biological Sciences. 2016. Vol. 23, no. 6, pp.731-735.
https://search.emarefa.net/detail/BIM-717178
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 735
Record ID
BIM-717178