Serum vaspin level in type 2 diabetic patients from Gaza Strip
العناوين الأخرى
مستوى الفازبين في مصل الدم لمرضى السكرى من النوع الثاني في قطاع غزة
مقدم أطروحة جامعية
مشرف أطروحة جامعية
al-Kahlut, Kamal al-Abd Muhammad
Yasin, Majid Muhammad
أعضاء اللجنة
al-Habibi, Mahmud Ismail
Abid, Abd Allah Assaf
الجامعة
الجامعة الإسلامية
الكلية
كلية العلوم
القسم الأكاديمي
قسم العلوم الحياتية
دولة الجامعة
فلسطين (قطاع غزة)
الدرجة العلمية
ماجستير
تاريخ الدرجة العلمية
2016
الملخص الإنجليزي
Background: Type 2 diabetes is prevalent in Gaza strip.
Recently, vaspin has been identified as interesting novel adipokine having insulin sensitizing effect.
However, the relationship between vaspin and type 2diabetes have not been adequately studied.
Objective: To assess serum vaspin level in type 2 diabetic patients from Gaza Strip, and its relationships with some biochemical variable.
Materials and methods: This case-control study comprised 88 type 2 diabetic patients (44 males and 44 females) and 88 healthy controls (44 males and 44 females).
Questionnaire interview was applied.
Serum vaspin, glucose, blood glycated hemoglobin (HbA1c), insulin, cholesterol, triglycerides, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), alanine aminotransferase (ALT), aspartate aminotransferase (AST), urea, creatinine and Homeostasis Model Assessment Insulin Resistance (HOMA-IR) were determined.
Data were computer analyzed using SPSS version 22.0.
Results: The mean ages of cases and controls were 45.9±7.1 and 45.8±7.0 years, respectively.
The mean level of vaspin was significantly higher in cases compared to controls (0.73±0.67 versus 0.47±0.43 ng/ml, P=0.033).
Obese diabetic patients showed higher vaspin levels compared to controls (0.99±0.7 versus 0.62±0.52 ng/ml, P=0.048).
Vaspin was also significantly increased in obese cases compared to non obese cases (0.99±0.7 versus 0.48±0.42 ng/ml, P=0.005).
The levels of blood HbA1c, serum glucose and HOMA-IR were significantly increased in cases compared to controls (6.7±1.3 versus 4.7±0.65%, P=0.000 and 189.6±79.1 versus 90.7±13.6 mg/dl, P=0.000, 8.0±7.3 versus 3.6±2.4, P=0.000, respectively).
The mean levels of triglycerides was significantly higher in cases compared to controls (187.6±133.8 versus 133.7±71.8 mg/dl, P=0.021) whereas HDL-C was significantly lower in cases (45.3±10.3 versus 50.8±13.8 mg/dl, P=0.039).
Serum vaspin levels showed significant positive correlations with BMI (r=0.280, P=0.008), HbA1c% (r=0.209, P=0.049), glucose (r=0.290, P =0.006 ), HOMA-IR (r=0.276, P=0.010), triglycerides (r=0.303, P=0.004) and ALT activity (r=0.434, P=0.000).
Conclusions: Serum vaspin was significantly higher in type 2 diabetic patients compared to controls.
Serum vaspin levels showed significant positive correlations with BMI, HbA1c, glucose, HOMA-IR, triglycerides and ALT.
التخصصات الرئيسية
عدد الصفحات
90
قائمة المحتويات
Table of contents.
Abstract.
Abstract in Arabic.
Chapter One : Introduction.
Chapter Two : Literature review.
Chapter Three : Materials and methods.
Chapter Four : Results.
Chapter Five : Discussion.
Chapter Six : Conclusion and recommendation.
References.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Burnu, Najwa Talal Khamis. (2016). Serum vaspin level in type 2 diabetic patients from Gaza Strip. (Master's theses Theses and Dissertations Master). Islamic University, Palestine (Gaza Strip)
https://search.emarefa.net/detail/BIM-727238
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Burnu, Najwa Talal Khamis. Serum vaspin level in type 2 diabetic patients from Gaza Strip. (Master's theses Theses and Dissertations Master). Islamic University. (2016).
https://search.emarefa.net/detail/BIM-727238
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Burnu, Najwa Talal Khamis. (2016). Serum vaspin level in type 2 diabetic patients from Gaza Strip. (Master's theses Theses and Dissertations Master). Islamic University, Palestine (Gaza Strip)
https://search.emarefa.net/detail/BIM-727238
لغة النص
الإنجليزية
نوع البيانات
رسائل جامعية
رقم السجل
BIM-727238
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر