Angiotensin II type 1 receptor gene A1166C polymorphism was not associated with acute coronary syndrome in an Iranian population
المؤلفون المشاركون
Delshad, Navid
Razavi Azarkhiavi, Kamal
Moohebati, Muhsin
Hassani, Mitra
Kasaian, Jamal
Etemadzadeh, Muhammad Rida
Alavi, Maryam Saadat
Behravan, Javad
Ghayour Mobarhan, Majid
Mirzaei, Hamid Reza
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 18، العدد 11 (30 نوفمبر/تشرين الثاني 2016)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2016-11-30
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
العلوم الطبية والصيدلة والعلوم الصحية
الملخص EN
Background : There are very limited data for Iranian populations on the predisposing genetic factors for acute coronary syndrome (ACS).
Objectives : The objective of the present study was to investigate the association of the angiotensin II type 1 receptor (AT1R) gene polymorphism and ACS in an Iranian population.
Patients and Methods : This cross-sectional study was conducted among 263 subjects (97 men and 166 women).
Patients (n = 128) aged 30 - 80 years with chest pain were recruited from the emergency department of Ghaem Hospital (Mashhad, Iran).
A 12-lead electrocardiograph plus creatine kinase MB (CK-MB) levels were used as the basis for the diagnosis of myocardial ischemia.
The control group was selected from age-matched healthy subjects (n = 135).
Non-enzymatic kits were used for extraction of DNA from blood samples.
Polymerase chain reaction (PCR) was performed to amplify the DNA fragments.
For restriction fragment length polymorphism (RFLP) determination, the DdeI enzyme was used to digest the amplified DNA fragments.
Statistical analyses were performed using SPSS version 13.0.
Results : There wasnostatistical difference in the genotype frequency of patients and healthy subjects with regard to age and gender (P > 0.05).
Conclusions : The AT1R A1166C polymorphism appeared not to be associated with the presence of ACS in the population studied.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Delshad, Navid& Ghayour Mobarhan, Majid& Mirzaei, Hamid Reza& Razavi Azarkhiavi, Kamal& Moohebati, Muhsin& Hassani, Mitra…[et al.]. 2016. Angiotensin II type 1 receptor gene A1166C polymorphism was not associated with acute coronary syndrome in an Iranian population. Iranian Red Crescent Medical Journal،Vol. 18, no. 11, pp.1-6.
https://search.emarefa.net/detail/BIM-728727
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Delshad, Navid…[et al.]. Angiotensin II type 1 receptor gene A1166C polymorphism was not associated with acute coronary syndrome in an Iranian population. Iranian Red Crescent Medical Journal Vol. 18, no. 11 (Nov. 2016), pp.1-6.
https://search.emarefa.net/detail/BIM-728727
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Delshad, Navid& Ghayour Mobarhan, Majid& Mirzaei, Hamid Reza& Razavi Azarkhiavi, Kamal& Moohebati, Muhsin& Hassani, Mitra…[et al.]. Angiotensin II type 1 receptor gene A1166C polymorphism was not associated with acute coronary syndrome in an Iranian population. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 11, pp.1-6.
https://search.emarefa.net/detail/BIM-728727
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5-6
رقم السجل
BIM-728727
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر