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Antibacterial activity of trigonella foenum-groecum essential oil against skin infection with staphylococcus aureus : in vitro and in vivo studies
المؤلفون المشاركون
Abbas, Ibrahim Salih
Abd al-Khaliq, Maysa Ali
Naji, Kawthar Abd al-Mahdi
Ajami, Ahmad Hamzah
Abu Raghif, Ahmad Rahmah
Kazim, Shuruq Rayyis
المصدر
al-Kindy College Medical Journal
العدد
المجلد 12، العدد 1 (30 يونيو/حزيران 2016)، ص ص. 1-8، 8ص.
الناشر
تاريخ النشر
2016-06-30
دولة النشر
العراق
عدد الصفحات
8
التخصصات الرئيسية
العلوم الاجتماعية (متداخلة التخصصات)
الملخص EN
Background: Multi- drug resistant (MDR) Staphylococcus aureus infections have become a major public health concern in both hospital and community settings.
Objective: to investigate the antibacterial activity of T.
Foenum- groecum essential oil against skin infection with S.
aureus and to study probable synergistic activity in combination with Clindamycin.
Type of the study: Cross-sectional study.
Methods:Antibacterial activity of T.
Foenum- groecum essential oil extract (1.2gm/100 μl) was investigated in multi- drug resistance (MDR) Staphylococcus aureus specimen isolated from patients with skin infection in Baghdad.
T.
Foenum- groecum use externally for cellulites and skin inflammation due to the presence of diosgenin .fast liquid chromatography was used to separate these components.
Results: Antibiotics combinations revealed that T.
Foenum- groecum essential oil with Clindamycin against MDR isolates of S.
aureus showed a synergistic effect when used as 1/4 MIC for each antimicrobial.
In vivo study was executed to determine antibacterial activity of these compounds by induction of skin infection with Staphylococcus aureus in mice and the treatment begun after 4hrs later and continue to seven days then skin biopsy was taken and sent for histopathological examination.
Conclusions: According to the results of this study, we can conclude that T.
Foenum- groecum essential oil has- emarkable antistaphylococcal activity.
Combination of T.
Foenum-groecum essential oil with Clindamycin was more effective than Clindamycin alone in treatment of skin infection with Staphylococcus aureus.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abu Raghif, Ahmad Rahmah& Kazim, Shuruq Rayyis& Abbas, Ibrahim Salih& Abd al-Khaliq, Maysa Ali& Naji, Kawthar Abd al-Mahdi& Ajami, Ahmad Hamzah. 2016. Antibacterial activity of trigonella foenum-groecum essential oil against skin infection with staphylococcus aureus : in vitro and in vivo studies. al-Kindy College Medical Journal،Vol. 12, no. 1, pp.1-8.
https://search.emarefa.net/detail/BIM-739673
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abu Raghif, Ahmad Rahmah…[et al.]. Antibacterial activity of trigonella foenum-groecum essential oil against skin infection with staphylococcus aureus : in vitro and in vivo studies. al-Kindy College Medical Journal Vol. 12, no. 1 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-739673
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abu Raghif, Ahmad Rahmah& Kazim, Shuruq Rayyis& Abbas, Ibrahim Salih& Abd al-Khaliq, Maysa Ali& Naji, Kawthar Abd al-Mahdi& Ajami, Ahmad Hamzah. Antibacterial activity of trigonella foenum-groecum essential oil against skin infection with staphylococcus aureus : in vitro and in vivo studies. al-Kindy College Medical Journal. 2016. Vol. 12, no. 1, pp.1-8.
https://search.emarefa.net/detail/BIM-739673
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes appendix : p. 6-8
رقم السجل
BIM-739673
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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