Antibacterial activity of trigonella foenum-groecum essential oil against skin infection with staphylococcus aureus : in vitro and in vivo studies
Joint Authors
Abbas, Ibrahim Salih
Abd al-Khaliq, Maysa Ali
Naji, Kawthar Abd al-Mahdi
Ajami, Ahmad Hamzah
Abu Raghif, Ahmad Rahmah
Kazim, Shuruq Rayyis
Source
al-Kindy College Medical Journal
Issue
Vol. 12, Issue 1 (30 Jun. 2016), pp.1-8, 8 p.
Publisher
University of Baghdad al-Kindi College of Medicine
Publication Date
2016-06-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Social Sciences (Multidisciplinary)
Abstract EN
Background: Multi- drug resistant (MDR) Staphylococcus aureus infections have become a major public health concern in both hospital and community settings.
Objective: to investigate the antibacterial activity of T.
Foenum- groecum essential oil against skin infection with S.
aureus and to study probable synergistic activity in combination with Clindamycin.
Type of the study: Cross-sectional study.
Methods:Antibacterial activity of T.
Foenum- groecum essential oil extract (1.2gm/100 μl) was investigated in multi- drug resistance (MDR) Staphylococcus aureus specimen isolated from patients with skin infection in Baghdad.
T.
Foenum- groecum use externally for cellulites and skin inflammation due to the presence of diosgenin .fast liquid chromatography was used to separate these components.
Results: Antibiotics combinations revealed that T.
Foenum- groecum essential oil with Clindamycin against MDR isolates of S.
aureus showed a synergistic effect when used as 1/4 MIC for each antimicrobial.
In vivo study was executed to determine antibacterial activity of these compounds by induction of skin infection with Staphylococcus aureus in mice and the treatment begun after 4hrs later and continue to seven days then skin biopsy was taken and sent for histopathological examination.
Conclusions: According to the results of this study, we can conclude that T.
Foenum- groecum essential oil has- emarkable antistaphylococcal activity.
Combination of T.
Foenum-groecum essential oil with Clindamycin was more effective than Clindamycin alone in treatment of skin infection with Staphylococcus aureus.
American Psychological Association (APA)
Abu Raghif, Ahmad Rahmah& Kazim, Shuruq Rayyis& Abbas, Ibrahim Salih& Abd al-Khaliq, Maysa Ali& Naji, Kawthar Abd al-Mahdi& Ajami, Ahmad Hamzah. 2016. Antibacterial activity of trigonella foenum-groecum essential oil against skin infection with staphylococcus aureus : in vitro and in vivo studies. al-Kindy College Medical Journal،Vol. 12, no. 1, pp.1-8.
https://search.emarefa.net/detail/BIM-739673
Modern Language Association (MLA)
Abu Raghif, Ahmad Rahmah…[et al.]. Antibacterial activity of trigonella foenum-groecum essential oil against skin infection with staphylococcus aureus : in vitro and in vivo studies. al-Kindy College Medical Journal Vol. 12, no. 1 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-739673
American Medical Association (AMA)
Abu Raghif, Ahmad Rahmah& Kazim, Shuruq Rayyis& Abbas, Ibrahim Salih& Abd al-Khaliq, Maysa Ali& Naji, Kawthar Abd al-Mahdi& Ajami, Ahmad Hamzah. Antibacterial activity of trigonella foenum-groecum essential oil against skin infection with staphylococcus aureus : in vitro and in vivo studies. al-Kindy College Medical Journal. 2016. Vol. 12, no. 1, pp.1-8.
https://search.emarefa.net/detail/BIM-739673
Data Type
Journal Articles
Language
English
Notes
Includes appendix : p. 6-8
Record ID
BIM-739673