Characterization of undifferentiated malignant spindle cell tumors : a practical immunohistochemical study in Kurdistan region, Iraq
العناوين الأخرى
توصيف الأورام الخبيثة غير المتمايزة ذات الخلايا مغزليه الشكل : دراسة نسيجية مناعية عملية في إقليم كردستان العراق
المؤلفون المشاركون
Pity, Intisar S.
Jalal, Jalal A.
Napaki, Sarbar ME.
المصدر
Journal of the Arab Board of Health Specializations
العدد
المجلد 13، العدد 4 (31 ديسمبر/كانون الأول 2012)، ص ص. 24-33، 10ص.
الناشر
المجلس العربي للاختصاصات الصحية
تاريخ النشر
2012-12-31
دولة النشر
سوريا
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Objective : The aim of this study was to evaluate the role of immunohistochemistry in characterization of undifferentiated malignant spindle cell tumors in Kurdistan region, Iraq.
Methods : The study extended from April 2008 to June 2010.
Overall, 102 cases were reported as undifferentiated malignant spindle cell tumors in the histopathology departments of Kurdistan region, Iraq.
Immunophenotyping done was streptavidin-biotin method on paraffin sections.
Results : In the studied sample, malignant spindle cell tumors were more frequently located in the bone and soft tissue (28.4 %), followed by gastrointestinal tract (17.6%) and respiratory tract (12.8 %), female genital tract formed (9.8 %), central nervous system (7.8 %), urinary tract (5.9 %), lymph nodes (4.9 %) and skin (3.9 %).
The remainder cases were (8.6 %) were miscellaneous.
Sarcoma group was at the top of the diagnosis list and the main bulk (50 %) followed by sarcomatoid carcinoma (10.8%), gastrointestinal stromal tumor (7.8 %) and melanoma (6.9 %).
Glioblastoma multiforme, malignant meningioma and mesothelioma were diagnosed in 2.9 % of cases each while monophasic Wilm’s tumor, yolk sac tumor and carcinosarcoma were found in 1.9 % of cases each.
by the increasing number of good quality antibodies in addition to the improvements in antigen retrieval techniques.8-13 Nonetheless, it is vital that the accuracy of clinical evaluation and morphologic differential diagnosis will definitely determine the success of IHC as a supplementary tool.1-8 In the current study, we present an overview of undifferentiated malignant spindle cell tumors in Kurdistan Region, Iraq with inconclusive clinico-morphological diagnosis and detail the immunohistochemical approach to these biopsies.
The occurrence of these tumors and the way in which they were distributed according to the localization were also evaluated
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pity, Intisar S.& Jalal, Jalal A.& Napaki, Sarbar ME.. 2012. Characterization of undifferentiated malignant spindle cell tumors : a practical immunohistochemical study in Kurdistan region, Iraq. Journal of the Arab Board of Health Specializations،Vol. 13, no. 4, pp.24-33.
https://search.emarefa.net/detail/BIM-747078
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pity, Intisar S.…[et al.]. Characterization of undifferentiated malignant spindle cell tumors : a practical immunohistochemical study in Kurdistan region, Iraq. Journal of the Arab Board of Health Specializations Vol. 13, no. 4 (2012), pp.24-33.
https://search.emarefa.net/detail/BIM-747078
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pity, Intisar S.& Jalal, Jalal A.& Napaki, Sarbar ME.. Characterization of undifferentiated malignant spindle cell tumors : a practical immunohistochemical study in Kurdistan region, Iraq. Journal of the Arab Board of Health Specializations. 2012. Vol. 13, no. 4, pp.24-33.
https://search.emarefa.net/detail/BIM-747078
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 32-33
رقم السجل
BIM-747078
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر