The evaluation of the relationship between serum levels of interleukin-6 and interleukin-10 and metabolic acidosis in hemodialysis patients
المؤلفون المشاركون
Zahed, Narges Sadat
Chehrazi, Saghar
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 28، العدد 1 (28 فبراير/شباط 2017)، ص ص. 23-29، 7ص.
الناشر
تاريخ النشر
2017-02-28
دولة النشر
السعودية
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Chronic kidney disease is defined as progressive kidney dysfunction.
The levels of various cytokines increase in hemodialysis (HD) patients.
High levels of interleukins (ILs) and presence of metabolic acidosis are described as independent risk factors for morbidity and mortality in these patients.
This study was designed to evaluate the relationship between IL-6 and IL-10 and serum bicarbonate and metabolic acidosis in HD patients.
In this analytical crosssectional study, patients referred to the HD units of Loghman Hakim and Shahid Ashrafi Esfahani Hospitals were randomly selected.
Demographic and laboratory data, such as albumin, creatinine, calcium, phosphorus, parathormone, C-reactive protein, complete blood count, ferritin, ILs-6 and -10, and arterial blood gas analysis, were recorded for each patient.
The correlation between IL and serum bicarbonate and other variables were evaluated by SPSS software.
The patients were compared for the presence of acidosis and positivity for IL.
A total of 84 patients with a mean age of 60.98 years and mean body mass index of 24.86 kg/m2 were evaluated (53% male and 57% female).
The mean dialysis duration was 24.86 ± 3.98 months.
Overall, 41.7% of the patients had diabetes mellitus and 36.9% of them had hypotension.
The mean serum levels of IL-6 and IL-10 were 6.036 and 17.46 pg/ml, respectively.
There was a significant correlation between IL-6 and IL-10 levels and serum bicarbonate and the incidence of metabolic acidosis (P <0.05).
Based on the results, metabolic acidosis and bicarbonate could be considered prognostic factors to differentiate the increased levels of IL-6 and IL-10 and associated morbidity and mortality.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zahed, Narges Sadat& Chehrazi, Saghar. 2017. The evaluation of the relationship between serum levels of interleukin-6 and interleukin-10 and metabolic acidosis in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 1, pp.23-29.
https://search.emarefa.net/detail/BIM-748863
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zahed, Narges Sadat& Chehrazi, Saghar. The evaluation of the relationship between serum levels of interleukin-6 and interleukin-10 and metabolic acidosis in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 1 (Jan. / Feb. 2017), pp.23-29.
https://search.emarefa.net/detail/BIM-748863
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zahed, Narges Sadat& Chehrazi, Saghar. The evaluation of the relationship between serum levels of interleukin-6 and interleukin-10 and metabolic acidosis in hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 1, pp.23-29.
https://search.emarefa.net/detail/BIM-748863
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 28-29
رقم السجل
BIM-748863
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر