Effect of matricaria Aurea ethanolic extract on skin inflammation and hematological and biochemical characteristics in the rats

العناوين الأخرى

تأثير المستخلص الإيثانولي لنبات البابونج على الالتهابات الجلدية و الخصائص الدموية و البيوكيمائية في الجرذان

مقدم أطروحة جامعية

al-Harub, Ahmad Sattam Muhammad

مشرف أطروحة جامعية

al-Shakhanbih, Jumah

أعضاء اللجنة

al-Shurafa, Khalid Yusuf Ahmad
Khulayfat, Khalid Muhammad
al-Harub, Amir Munawwir

الجامعة

جامعة مؤتة

الكلية

كلية العلوم

القسم الأكاديمي

قسم الأحياء

دولة الجامعة

الأردن

الدرجة العلمية

ماجستير

تاريخ الدرجة العلمية

2017

الملخص الإنجليزي

The effect of oral administration of ethanolic extract of aerial parts of Matricaria aurea on acute skin inflammation, hematological and serum biochemical parameters were investigated in albino rats.

This study was intended to evaluate the anti-inflammatory activity in carrageenan induced paw oedema.

Rats were divided into two groups, control group and treated group.

The treated rats were orally given 200 mg/kg body weight of ethanolic extract of M.

aurea for 4 weeks.

For antiinflammatory activity test, both groups were injected with 0.1 ml of 1% lambda carrageenan in saline , and the degree of paw oedema was assessed.

The results of the present study showed a non significant (P>0.05) change in RBCs count, hematocrit, WBCs count, differential WBCs count, serum levels of cholesterol, triglycerides, HDL, LDL, alanine aminotransferase (ALT), glucose and uric acid.

Other parameters including albumin, creatinine, AST and total protein were significantly (P<0.05) increased as compared to control rats.

However, hemoglobin and alkaline phosphatase levels were significantly decreased (P<0.05).

On the other hand the ethanolic extract of M.

aurea didn't show inhibition on carrageenan induced rat paw oedema.

It is concluded that chronic treatment with ethanolic extract of M.

aurea induces significant changes in some hematological and biochemical parameters of the rat blood.

In addition, the ethanolic extract of M.

aurea didn't show anti-inflammatory activity in the rat skin.

التخصصات الرئيسية

الأحياء

الموضوعات

عدد الصفحات

48

قائمة المحتويات

Table of contents.

Abstract.

Abstract in Arabic.

Chapter One : Theoretical background.

Chapter Two : Literature review.

Chapter Three : Design and methodology.

Chapter Four : Results, discussion and recommendation results.

References.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

al-Harub, Ahmad Sattam Muhammad. (2017). Effect of matricaria Aurea ethanolic extract on skin inflammation and hematological and biochemical characteristics in the rats. (Master's theses Theses and Dissertations Master). Mutah University, Jordan
https://search.emarefa.net/detail/BIM-749125

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

al-Harub, Ahmad Sattam Muhammad. Effect of matricaria Aurea ethanolic extract on skin inflammation and hematological and biochemical characteristics in the rats. (Master's theses Theses and Dissertations Master). Mutah University. (2017).
https://search.emarefa.net/detail/BIM-749125

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

al-Harub, Ahmad Sattam Muhammad. (2017). Effect of matricaria Aurea ethanolic extract on skin inflammation and hematological and biochemical characteristics in the rats. (Master's theses Theses and Dissertations Master). Mutah University, Jordan
https://search.emarefa.net/detail/BIM-749125

لغة النص

الإنجليزية

نوع البيانات

رسائل جامعية

رقم السجل

BIM-749125