Effects of soybean oligosaccharides on intestinal microbial communities and immune modulation in mice
المؤلفون المشاركون
Wu, Xingzhuang
Giovanni, Vigna
Meng, Xianjun
Ma, Yan
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 24، العدد 1 (31 يناير/كانون الثاني 2017)، ص ص. 114-121، 8ص.
الناشر
تاريخ النشر
2017-01-31
دولة النشر
السعودية
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Soybean oligosaccharides (SBOSs) are potential prebiotics that may be used to improve immune function.
Here, we investigated the effects of intragastric administration of SBOSs in mice to determine the effects on autochthonous intestinal microbial communities and immunological parameters.
Results E: After 22-day administration, 4.0 g kg body weight (BW)^1 SBOSs significantly enhanced the proliferation of bifidobacteria and lactic acid bacteria (LAB) as compared to the control.
This dose of SBOSs also significantly increased numbers of ente-rococci and decreased numbers of Clostridium perfringens.
Treatment with 4.0 g kg BW^1 SBOSs also significantly increased the percentage of T-lymphocytes and lymphocyte proliferation as compared to the control, suggesting that SBOSs promoted cellular immunity in mice.
Additionally, 4.0gkgBW^1 SBOSs induced significant differences in hemolysin production, natural killer (NK) cell activity, phagocytic activity, cytokine production, and immunoglobulin levels compared to the control.
Conclusion: Our data demonstrated that intragastric administration of SBOSs at a dose of 4.0 g kg BW^1 improved the numbers of beneficial intestinal microbes and enhanced immunological function of mice.
Therefore, these data supported that SBOSs may have applications as a prebiotic to improve immune responses in humans.
Further studies are warranted.
© 2016 The Authors.
Production and hosting by Elsevier B.V.
on behalf of King Saud University.
This is
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ma, Yan& Wu, Xingzhuang& Giovanni, Vigna& Meng, Xianjun. 2017. Effects of soybean oligosaccharides on intestinal microbial communities and immune modulation in mice. Saudi Journal of Biological Sciences،Vol. 24, no. 1, pp.114-121.
https://search.emarefa.net/detail/BIM-753671
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ma, Yan…[et al.]. Effects of soybean oligosaccharides on intestinal microbial communities and immune modulation in mice. Saudi Journal of Biological Sciences Vol. 24, no. 1 (Jan. 2017), pp.114-121.
https://search.emarefa.net/detail/BIM-753671
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ma, Yan& Wu, Xingzhuang& Giovanni, Vigna& Meng, Xianjun. Effects of soybean oligosaccharides on intestinal microbial communities and immune modulation in mice. Saudi Journal of Biological Sciences. 2017. Vol. 24, no. 1, pp.114-121.
https://search.emarefa.net/detail/BIM-753671
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 120-121
رقم السجل
BIM-753671
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر