Protective effect of olive and juniper leaves extracts on nephrotoxicity induced by thioacetamide in male mice
المؤلفون المشاركون
al-Rubai, Ali A.
al-Malki, Daklallah A.
al-Attar, Atif M.
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 24، العدد 1 (31 يناير/كانون الثاني 2017)، ص ص. 15-22، 8ص.
الناشر
تاريخ النشر
2017-01-31
دولة النشر
السعودية
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
This study, for the first time, evaluates the effect of olive and juniper leaves extracts and their combination on thioacetamide (TAA)-induced nephrotoxicity in male mice.
The experimental mice were divided into eight groups.
Group 1 was served as control.
Group 2 was exposed to TAA.
Group 3 was treated with TAA and olive leaves extract.
Group 4 was subjected to TAA and juniper leaves extract.
Group 5 was exposed to TAA and olive and juniper leaves extracts.
Groups 6, 7 and 8 were treated with olive, juniper, and olive and juniper leaves extracts respectively.
In mice treated with only TAA, significant increases of blood urea nitrogen and uric acid were observed after six weeks.
Moreover, levels of serum creatinine, blood urea nitrogen and uric acid were statistically increased in mice administrated with only TAA for twelve weeks.
Insignificant alterations in levels of these haematobiochemical parameters were noted in other treated groups after six and twelve weeks.
Histopathological evaluations of renal sections from mice treated with only TAA for twelve weeks showed severe damage of the renal corpuscles.
Furthermore, the renal sections from mice treated with TAA and olive leaves extract, TAA and juniper leaves extract, TAA and olive and juniper leaves extracts, olive leaves extract, juniper leaves extract, and olive and juniper leaves extracts showed normal structures.
In addition, it is conceivable therefore, that these extracts exhibit protective influences against TAA-induced nephrotoxicity, probably mediated through the antioxidative pathway roles.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Attar, Atif M.& al-Rubai, Ali A.& al-Malki, Daklallah A.. 2017. Protective effect of olive and juniper leaves extracts on nephrotoxicity induced by thioacetamide in male mice. Saudi Journal of Biological Sciences،Vol. 24, no. 1, pp.15-22.
https://search.emarefa.net/detail/BIM-753853
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Attar, Atif M.…[et al.]. Protective effect of olive and juniper leaves extracts on nephrotoxicity induced by thioacetamide in male mice. Saudi Journal of Biological Sciences Vol. 24, no. 1 (Jan. 2017), pp.15-22.
https://search.emarefa.net/detail/BIM-753853
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Attar, Atif M.& al-Rubai, Ali A.& al-Malki, Daklallah A.. Protective effect of olive and juniper leaves extracts on nephrotoxicity induced by thioacetamide in male mice. Saudi Journal of Biological Sciences. 2017. Vol. 24, no. 1, pp.15-22.
https://search.emarefa.net/detail/BIM-753853
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 21-22
رقم السجل
BIM-753853
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر