Risk factors of rheumatoid arthritis development among females in north-west of Iran : a case-control study

المؤلفون المشاركون

Shishavan, Neda Ghamarzad
Pirouzpanah, Said
Hajialilo, Mehrzad
Khabbazi, Ali Rida
Jafarpour, Farnaz
Mirtaheri, Ilham
Farrin, Nazila
Ibrahim Zadih, Sima
Baban, Navid
Shakiba, Zahra
Ghahreman Zadeh, Kazim

المصدر

Iranian Red Crescent Medical Journal

العدد

المجلد 18، العدد 12 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.

الناشر

المستشفى الإيراني

تاريخ النشر

2016-12-31

دولة النشر

الإمارات العربية المتحدة

عدد الصفحات

8

التخصصات الرئيسية

الطب البشري

الملخص EN

Background: Given the high prevalence of rheumatoid arthritis (RA) in females of reproductive ages, it seems that hormonal factors might be important in RA pathogenesis.

Objectives: The current study aimed to investigate the association between females’ reproductive factors occurring prior to the onset of rheumatoid arthritis and the risk of RA development.

Methods: This case-control study was conducted on 231 patients with RA and 238 controls among females aged 26 - 64 years old from the North-West of Iran.

The adjusted risk of RA was assessed using multivariate logistic regression models.

Results: Females 14 years old at menarche, were more likely to be at risk of RA (OR = 1.69; 95%CI: 1.08 - 2.64).

Advanced maternal age at first delivery (OR = 1.91; 95%CI: 1.21 - 3.26) and having abortion (OR = 1.97; 95%CI: 1.23 - 2.99) significantly increased the risk of RA.

Post-menopausal status increased the risk of developing RA (OR = 2.97; 95%CI: 1.98 - 4.46).

Longer duration of breast-feeding was determined as significant protective variable for RA (P < 0.05).

Subjects with oral contraceptives (OCs) use (OR = 0.36; 95% CI: 0.20 - 0.64), parity (OR = 0.20; 95%CI: 0.06 - 0.70) or large number of children tended to show rather more reduced risk of RA.

Conclusions: The risk of RA increased with delayed menarche, advanced maternal age at first delivery and early age at menopause.

However, longer duration of breast-feeding, parity, large number of children and consumption of OCs were found as protective independent variables against RA

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Shishavan, Neda Ghamarzad& Pirouzpanah, Said& Hajialilo, Mehrzad& Khabbazi, Ali Rida& Jafarpour, Farnaz& Mirtaheri, Ilham…[et al.]. 2016. Risk factors of rheumatoid arthritis development among females in north-west of Iran : a case-control study. Iranian Red Crescent Medical Journal،Vol. 18, no. 12, pp.1-8.
https://search.emarefa.net/detail/BIM-758405

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Shishavan, Neda Ghamarzad…[et al.]. Risk factors of rheumatoid arthritis development among females in north-west of Iran : a case-control study. Iranian Red Crescent Medical Journal Vol. 18, no. 12 (Dec. 2016), pp.1-8.
https://search.emarefa.net/detail/BIM-758405

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Shishavan, Neda Ghamarzad& Pirouzpanah, Said& Hajialilo, Mehrzad& Khabbazi, Ali Rida& Jafarpour, Farnaz& Mirtaheri, Ilham…[et al.]. Risk factors of rheumatoid arthritis development among females in north-west of Iran : a case-control study. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 12, pp.1-8.
https://search.emarefa.net/detail/BIM-758405

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 7-8

رقم السجل

BIM-758405