Evaluation of disease activity markers in relation to dry eye disease in patients with rheumatoid arthritis
المؤلفون المشاركون
Abd al-Aziz, Dua M.
al-Mahdi, Amirah R.
Abd al-Rahim, Samiyah M.
Ubayd, Wiam M.
al-Kitkat, Raniya S.
al-Badawi, Muhjah A.
المصدر
Egyptian Rheumatology and Rehabilitation
العدد
المجلد 44، العدد 3 (30 سبتمبر/أيلول 2017)، ص ص. 111-117، 7ص.
الناشر
الجمعية المصرية للروماتيزم و التأهيل
تاريخ النشر
2017-09-30
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Purpose The aim of this study was to correlate the presence of anti-cyclic citrullinated peptide (anti-CCP) and anti-mutated citrullinated vimentin (anti-MCV) antibodies with rheumatoid disease activity and dry eye disease in patients with rheumatoid arthritis (RA).
Patients and methods A total of 69 patients were evaluated for the activity of RA using the Disease Activity Score (DAS-28), erythrocyte sedimentation rate, and C-reactive protein.
We used the Health Assessment Questionnaire-Disability Index to assess functional disability.
Anti-CCP and anti-MCV antibodies were measured using enzymelinked immunosorbent assay technique.
We assessed dry eye symptoms using Ocular Surface Disease Index (OSDI) questionnaire.
Clinical tests used for dry eye assessment included Schirmer’s test, tear breakup time test, and ocular surface fluorescein staining.
Results Anti-CCP antibody serumlevels significantly correlated withDAS (r=0.46, P=0.036), Schirmer’s test (r=0.40, P=0.038), and ocular surface fluorescein staining (r=0.6, P=0.04).
Anti-MCV antibody serum levels correlated with DAS (r=0.5, P=0.04), ocular surface fluorescein staining (r=0.9, P=0.007), and OSDI score (r=0.3, P=0.03).
DAS showed a nonsignificant correlation with OSDI score and all tests of dry eye.
OSDI score significantly correlated with Schirmer’s test (P=0.036).
Conclusion Dry eye is themost common ocularmanifestation inour investigated patients with RA.
Dry eye disease existence is not correlated with disease activity, hence all patients with RA should be regularly examined for dye eye regardless of disease severity.
Rheumatologists could use the OSDI questionnaire for screening dry eye disease in patientswithRA.
The presence of anti-CCPand anti-MCVantibodies maydenote the existence of dry eye disease and correlates with RA disease activity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Badawi, Muhjah A.& al-Mahdi, Amirah R.& Abd al-Rahim, Samiyah M.& Ubayd, Wiam M.& al-Kitkat, Raniya S.& Abd al-Aziz, Dua M.. 2017. Evaluation of disease activity markers in relation to dry eye disease in patients with rheumatoid arthritis. Egyptian Rheumatology and Rehabilitation،Vol. 44, no. 3, pp.111-117.
https://search.emarefa.net/detail/BIM-760711
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Badawi, Muhjah A.…[et al.]. Evaluation of disease activity markers in relation to dry eye disease in patients with rheumatoid arthritis. Egyptian Rheumatology and Rehabilitation Vol. 44, no. 3 (Jul. / Sep. 2017), pp.111-117.
https://search.emarefa.net/detail/BIM-760711
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Badawi, Muhjah A.& al-Mahdi, Amirah R.& Abd al-Rahim, Samiyah M.& Ubayd, Wiam M.& al-Kitkat, Raniya S.& Abd al-Aziz, Dua M.. Evaluation of disease activity markers in relation to dry eye disease in patients with rheumatoid arthritis. Egyptian Rheumatology and Rehabilitation. 2017. Vol. 44, no. 3, pp.111-117.
https://search.emarefa.net/detail/BIM-760711
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 115-117
رقم السجل
BIM-760711
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر