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Dexmedetomidine versus clonidine as an adjuvant to peribulbar block in vitreoretinal surgery
المؤلفون المشاركون
al-Kabariti, Rim H.
Khashabah, Muhammad Y.
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 5، العدد 3 (30 سبتمبر/أيلول 2012)، ص ص. 288-294، 7ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2012-09-30
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
To assess the efficacy, time to first analgesic request, total analgesic requirement, patients’ satisfaction, intraocular pressure (IOP), and side effects of addition of dexmedetomidine to a local anesthetic mixture for a peribulbar block in vitreoretinal surgery.
Methods A double-blind prospective study was carried out on 50 ASA I and II patients scheduled for elective vitreoretinal surgery.
Patients were divided randomly into two groups, 25 patients in each group.
Group C received equal volumes of 9 ml of a 1 : 1 mixture of bupivacaine 0.5% and lidocaine 2% with 1 mg/kg clonidine in 1 ml saline and group D received the same local anesthetic mixture supplemented with 1 mg/kg dexmedetomidine in 1 ml saline (total volume 10 ml).
The duration and onset of sensory and motor block, time to first analgesic request, total analgesic requirement, patients’ comfort, IOP, and other side effects of dexmedetomidine were assessed.
Results Patients who received dexmedetomidine showed significantly prolonged duration of lid, globe akinesia, and globe anesthesia (192.0 ± 34.9, 229.5 ±58.5, and 130.9 ± 30.5 min, respectively).
The measurement of IOP was significantly less in the dexmedetomidine group after 5 and 10 min.
The time to first analgesic requirement was statistically higher in the dexmedetomidine group (6.2 ±2.3 h), whereas the total analgesic requirement was significantly higher in the clonidine group.
More than 90% of dexmedetomidine patients were comfortable intraoperatively and postoperatively, with significantly less side effects of dryness of the mouth and dizziness.
Conclusion The addition of 1 mg/kg dexmedetomidne to the lidocaine–bupivacaine mixture in a peribulbar block for vitreoretinal surgery improves the duration of lid, globe akinesia, and anesthesia, with a significant decrease in the IOP.
It prolongs the time to first rescue analgesia and decreases the number of analgesic requirements, with minimal side effects in comparison with clonidine
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Kabariti, Rim H.& Khashabah, Muhammad Y.. 2012. Dexmedetomidine versus clonidine as an adjuvant to peribulbar block in vitreoretinal surgery. Ain Shams Journal of Anesthesiology،Vol. 5, no. 3, pp.288-294.
https://search.emarefa.net/detail/BIM-761542
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Kabariti, Rim H.& Khashabah, Muhammad Y.. Dexmedetomidine versus clonidine as an adjuvant to peribulbar block in vitreoretinal surgery. Ain Shams Journal of Anesthesiology Vol. 5, no. 3 (Sep. 2012), pp.288-294.
https://search.emarefa.net/detail/BIM-761542
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Kabariti, Rim H.& Khashabah, Muhammad Y.. Dexmedetomidine versus clonidine as an adjuvant to peribulbar block in vitreoretinal surgery. Ain Shams Journal of Anesthesiology. 2012. Vol. 5, no. 3, pp.288-294.
https://search.emarefa.net/detail/BIM-761542
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 293-294
رقم السجل
BIM-761542
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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