Effect of growth hormone on final height in children with idiopathic short stature : A UAE, eastern region experience
المؤلفون المشاركون
Shadid, Faris
Mreish, Shirin
Kaplan, Walid
المصدر
العدد
المجلد 32، العدد 6 (30 نوفمبر/تشرين الثاني 2017)، ص ص. 403-406، 4ص.
الناشر
المجلس العماني للاختصاصات الطبية
تاريخ النشر
2017-11-30
دولة النشر
سلطنة عمان
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Objectives: The use of growth hormone (GH) in idiopathic short stature (ISS) has been a subject of debate for the past two decades.
We sought to assess the effect of GH on final height (FH) in patients with ISS in our region, which has a high consanguinity rate, and compare it to the effect observed in GH deficient (GHD) patients.
Methods: We conducted a retrospective chart review from 1 January 2005 to 31 December 2013 for patients with ISS or GHD from the local United Arab Emirates population who received GH treatment and were followed-up regularly in our clinic.
The change in height Z-score at 12 months and FH were assessed within each group and between the two groups.
Results: Twenty-one patients with ISS and 29 patients with GHD were studied.
There was a significant change in height Z-score at 12 months and FH in both groups (p < 0.001).
The improvement in the ISS group was comparable to the response seen in GHD patients at 12 months (0.5±0.3 standard deviation score (SDS), and 0.5±0.4 SDS, respectively; p = 0.540).
The effect on FH was better in ISS group than the GHD group of all etiologies (1.3±0.6 SDS vs.
0.9±0.7 SDS, respectively; p = 0.050), there was no difference between the ISS and the subgroup of idiopathic GHD (1.3±0.5 SDS and 1.2±0.8 SDS, respectively).
Conclusions: In our local population, GH has a positive effect on the short-term growth and FH of children with ISS to the same extent that has been observed in children with idiopathic GH deficiency
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mreish, Shirin& Kaplan, Walid& Shadid, Faris. 2017. Effect of growth hormone on final height in children with idiopathic short stature : A UAE, eastern region experience. Oman Medical Journal،Vol. 32, no. 6, pp.403-406.
https://search.emarefa.net/detail/BIM-772629
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mreish, Shirin…[et al.]. Effect of growth hormone on final height in children with idiopathic short stature : A UAE, eastern region experience. Oman Medical Journal Vol. 32, no. 6 (Nov. 2017), pp.403-406.
https://search.emarefa.net/detail/BIM-772629
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mreish, Shirin& Kaplan, Walid& Shadid, Faris. Effect of growth hormone on final height in children with idiopathic short stature : A UAE, eastern region experience. Oman Medical Journal. 2017. Vol. 32, no. 6, pp.403-406.
https://search.emarefa.net/detail/BIM-772629
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 406
رقم السجل
BIM-772629
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر