Enhancing antidiabetic and antimicrobial performance of Ocimum basilicum, and Ocimum sanctum (L.) using silver nanoparticles
المؤلفون المشاركون
Malapermal, Veshara
Botha, Izel
Krishna, Suresh Babu Naidu
Mbatha, Joyce Nonhlanhla
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 24، العدد 6 (30 سبتمبر/أيلول 2017)، ص ص. 1294-1305، 12ص.
الناشر
تاريخ النشر
2017-09-30
دولة النشر
السعودية
عدد الصفحات
12
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الملخص EN
The role of silver nanoparticles (AgNps) is an attractive proposition for advancing modern diabetes therapies and applied science.
Stable AgNps with a size range of 3–25 nm were synthesized using aqueous leaf extracts from Ocimum basilicum, Ocimum sanctum, and in combination.
The concentration of the extracts facilitated the reduction of silver nitrate that led to the rapid formation of AgNps at room temperature, indicating a higher reaction rate as opposed to harsh chemical methods, and high conversion energy usually involved in the synthesis.
The size, shape and elemental analysis were carried out using UV–Visible spectroscopy, transmission electron microscopy (TEM), scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM–EDX), dynamic light scattering (DLS), and zeta potential whilst, Fourier transform infrared (FTIR) supported by gas chromatography mass spectroscopy (GC–MS) was used to identify the type of capping agents.
Inhibition of a-amylase and a-glucosidase enzymes retards the rate of carbohydrate digestion, thereby provides an alternative and a less evasive strategy of reducing postprandial hyperglycaemia in diabetic patients.
The AgNps derived from O.
sanctum and O.
basilicum, respectively displayed an inhibitory effect at 89.31 ± 5.32%, and 79.74± 9.51%, respectively, against Bacillus stearothermophilus a-glucosidase enzyme model, indicating an enhanced biocatalytic potential compared to their respective crude extracts and the control.
Furthermore, the emerging rate of infections in diabetic patients validates the need for the discovery of dual diabetes therapies.
As a result, the bioderived AgNps displayed antimicrobial activity against bacterial
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Malapermal, Veshara& Botha, Izel& Krishna, Suresh Babu Naidu& Mbatha, Joyce Nonhlanhla. 2017. Enhancing antidiabetic and antimicrobial performance of Ocimum basilicum, and Ocimum sanctum (L.) using silver nanoparticles. Saudi Journal of Biological Sciences،Vol. 24, no. 6, pp.1294-1305.
https://search.emarefa.net/detail/BIM-776411
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Malapermal, Veshara…[et al.]. Enhancing antidiabetic and antimicrobial performance of Ocimum basilicum, and Ocimum sanctum (L.) using silver nanoparticles. Saudi Journal of Biological Sciences Vol. 24, no. 6 (Sep. 2017), pp.1294-1305.
https://search.emarefa.net/detail/BIM-776411
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Malapermal, Veshara& Botha, Izel& Krishna, Suresh Babu Naidu& Mbatha, Joyce Nonhlanhla. Enhancing antidiabetic and antimicrobial performance of Ocimum basilicum, and Ocimum sanctum (L.) using silver nanoparticles. Saudi Journal of Biological Sciences. 2017. Vol. 24, no. 6, pp.1294-1305.
https://search.emarefa.net/detail/BIM-776411
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 1303-1305
رقم السجل
BIM-776411
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر