Serum level of interleukin-22 in patients with psoriasis and its correlation with disease severity
المؤلفون المشاركون
Hasab Allah, Ashraf
Twisy, Huwayda
Hufni, Iman R. M.
Mursi, Hanan
المصدر
Journal of Current Medical Research and Practice
العدد
المجلد 2، العدد 2 (31 أغسطس/آب 2017)، ص ص. 133-135، 3ص.
الناشر
تاريخ النشر
2017-08-31
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Introduction Psoriasis is a Tcellmediated inflammatory disease where Thelper (Th) lymphocytes (Th1, Th17, and Th22) play an important role in its pathogenesis.
The aim of the present study was to assess the serum levels of interleukin (IL)22 and its correlation with disease severity.
Materials and methods The present study included 25 psoriatic patients and 25 healthy controls.
Using serum samples collected from psoriatic patients and healthy controls, the concentrations of IL‑22 were examined using ELISA kits.
The severity of psoriatic skin lesions was assessed using psoriasis area and severity index scores.
Results IL‑22 concentrations were significantly higher in psoriatic patients in comparison with the control group.
A significant, positive correlation between the concentrations of IL‑22 and the severity of psoriasis was found.
Conclusion The results of our study suggest that Th22 along with its cytokine responses may contribute to the skin and systemic inflammatory conditions characteristic of psoriasis.
It seems that early identification of soluble biomarkers and initiation of wellmatched treatment may prevent exacerbation and progression of psoriasis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hufni, Iman R. M.& Mursi, Hanan& Hasab Allah, Ashraf& Twisy, Huwayda. 2017. Serum level of interleukin-22 in patients with psoriasis and its correlation with disease severity. Journal of Current Medical Research and Practice،Vol. 2, no. 2, pp.133-135.
https://search.emarefa.net/detail/BIM-788339
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hufni, Iman R. M.…[et al.]. Serum level of interleukin-22 in patients with psoriasis and its correlation with disease severity. Journal of Current Medical Research and Practice Vol. 2, no. 2 (May. / Aug. 2017), pp.133-135.
https://search.emarefa.net/detail/BIM-788339
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hufni, Iman R. M.& Mursi, Hanan& Hasab Allah, Ashraf& Twisy, Huwayda. Serum level of interleukin-22 in patients with psoriasis and its correlation with disease severity. Journal of Current Medical Research and Practice. 2017. Vol. 2, no. 2, pp.133-135.
https://search.emarefa.net/detail/BIM-788339
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 135
رقم السجل
BIM-788339
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر