Effects of replacing high fat diet by low fat high-protein diet supplemented with two levels of unripe bananas powder and its peels on obese rats

الملخص EN

This study was undertaken to determine whether replacing from high fat diet by low fat - high protein diet fortified with two levels of unripe bananas powder and its peels would alter the quantity of lipid fraction, liver enzymes, leptin hormone and glucose of rats suffering from obesity.

Two main experimental groups of rats were used in this experiment.

The first main group (6 rats) were fed on basal diet as a control negative, while the second main group (42 rats) were fed on high fat diet (for 6 weeks) to induce obesity.

Then, the second main group was divided into seven subgroups (n = 6) according to the following: Subgroup 1: fed on high fat diet (HFD) as a control positive group, subgroup (2): was fed on low fat diet (LFD).

Subgroup (3): was fed on low fat and high protein diet (LF) and (HPD).

Subgroups (4 and 5): were fed on LF and HPD (containing 3% and 6% unripe banana powder flour, respectively).

Subgroup (6 and 7): were fed on LF and HPD (containing 3% and 6% banana peels powder, respectively).

Feeding rats on (HFD) induced defectiveness in lipid profile, leptin hormone, glucose and liver enzymes.

Feeding obese rats with LF & HP diets containing the two levels from unripe banana and its peels (3 & 6%) led to decrease in body weight gain, serum biomarkers (i.e.

cholesterol, triglycerides, low & very low density lipoprotein, leptin, glucose and liver enzymes) significantly, while high density lipoprotein increased significantly (p< 0.05), as compared to the positive control group fed on HFD, obese group fed on LFD and obese group fed on LF&HPD.

In conclusion, feeding obese rats with LF & HPD supplemented with unripe banana and banana peels resulted in significant reduction in body weight gain and blood lipids.