Association of insulin growth factor-1 and growth hormone levels in elderly renal transplant recipients with cardiac dysfunction
المؤلفون المشاركون
Sadiq, Khalid M.
Sulayman, Amin R.
Sulayman, Mahmud A.
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 30، العدد 1 (28 فبراير/شباط 2019)، ص ص. 62-67، 6ص.
الناشر
تاريخ النشر
2019-02-28
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Insulin growth factor-1 (IGF-1) and growth hormone (GH) have cardiac protective effects through many mechanisms; they can directly oppose endothelial dysfunction in a number of ways.
Many studies assessed the effect of GH or IGF-like growth factor 1 in patients with cardiac dysfunction, but no previous study assessed the GH and insulin-like growth factor-1 in renal transplant recipients with and without cardiac dysfunction, especially elderly.
Eighty patients with renal transplantation and age limit above 75 years.
They were subdivided into two groups according to the presence or absence of cardiac dysfunction based on medical history, clinical findings, electrocardiogram, and echocardiography.
Serum GH and insulin-like growth factor-1 were studied by immunoradiometric assay.
The echocardiography study was performed.
M-mode two-dimensional and Doppler measurements were taken to obtain the four- and five- chamber views, chambers’ dimensions, left ventricular end-diastolic dimensions, left ventricular end-systolic dimensions, septal wall thickness (SWT), distance between leading edges of the endocardial and pericardial echoes of left ventricular posterior wall (posterior wall thickness), aortic root and left atrial dimensions (LAD), fractional shortening and ejection fraction.
IGF-1 is lower in patients with cardiac dysfunction with renal transplantation with mean value of 61 ± 30.05 than those control group with mean value 145.52 ± 70.5.
Level of human growth factor is higher in patients with dysfunction with renal transplantation with mean value 2.62 ± 3.05 than those control group after renal transplantation with mean value 0.85 ± 0.9.
No correlations were found between IGF-1 and various echocardiographic parameters.
Only SWT and LAD were negatively correlated with GH, r = −0.08, P ˂0.02, r = −0.37, P ˂0.03, respectively.
No correlation was found between IGF-1 and various echocardiographic parameters.
Only SWT and LAD were negatively correlated with GH
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sulayman, Amin R.& Sulayman, Mahmud A.& Sadiq, Khalid M.. 2019. Association of insulin growth factor-1 and growth hormone levels in elderly renal transplant recipients with cardiac dysfunction. Saudi Journal of Kidney Diseases and Transplantation،Vol. 30, no. 1, pp.62-67.
https://search.emarefa.net/detail/BIM-887115
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sulayman, Amin R.…[et al.]. Association of insulin growth factor-1 and growth hormone levels in elderly renal transplant recipients with cardiac dysfunction. Saudi Journal of Kidney Diseases and Transplantation Vol. 30, no. 1 (Jan. / Feb. 2019), pp.62-67.
https://search.emarefa.net/detail/BIM-887115
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sulayman, Amin R.& Sulayman, Mahmud A.& Sadiq, Khalid M.. Association of insulin growth factor-1 and growth hormone levels in elderly renal transplant recipients with cardiac dysfunction. Saudi Journal of Kidney Diseases and Transplantation. 2019. Vol. 30, no. 1, pp.62-67.
https://search.emarefa.net/detail/BIM-887115
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 67
رقم السجل
BIM-887115
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر