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Hepatitis C virus-induced glomerular disease and posterior reversible encephalopathy syndrome after liver transplant : case report and literature review
المؤلفون المشاركون
Paolucci, Aldo
Antonelli, Barbara
Cerutti, Roberta
Donato, Francesca Maria
Lampertico, Pietro
Messa, Piergiorgio
Fabrizi, Fabrizio
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 30، العدد 1 (28 فبراير/شباط 2019)، ص ص. 239-249، 11ص.
الناشر
تاريخ النشر
2019-02-28
دولة النشر
السعودية
عدد الصفحات
11
التخصصات الرئيسية
الموضوعات
الملخص EN
Chronic hepatitis C virus (HCV) infection is associated with numerous extra- hepatic complications, including neurological and renal manifestations.
We describe the case of a 67-year-old Caucasian man with HCV-associated cryoglobulinemic glomerulonephritis, cirrhosis, and hepatocellular carcinoma.
The early posttransplant course was complicated by fibrosing cholestatic hepatitis due to recurrent HCV in the graft (HCV RNA up to 44,944,438 IU/mL).
Proliferative glomerulonephritis (nephritic and nephrotic syndrome) with mixed cryoglobulinemia (purpura) was also recorded.
Seventy-two days after surgery, the patient presented with seizures and arterial hypertension; brain magnetic resonance imaging indicated the diagnosis of posterior reversible encephalopathy syndrome (PRES).
PRES responded well to medical treatment with complete resolution of neurological changes.
Antiviral therapy (sofosbuvir and ribavirin, six months) gave a sustained viral response with the improvement of cryoglobulinemic symptoms (including glomerular disease).
Repeat liver biopsy revealed the regression of cholestatic damage and perisinusoidal fibrosis.
The current follow-up shows stable chronic renal failure (serum creatinine: 1.4 mg/dL) and mild nephritic syndrome.
The impact of extrahepatic manifestations of HCV on patient outcomes is highlighted from novel observational studies reporting a relationshipa diseases are underway
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fabrizi, Fabrizio& Paolucci, Aldo& Antonelli, Barbara& Cerutti, Roberta& Donato, Francesca Maria& Lampertico, Pietro…[et al.]. 2019. Hepatitis C virus-induced glomerular disease and posterior reversible encephalopathy syndrome after liver transplant : case report and literature review. Saudi Journal of Kidney Diseases and Transplantation،Vol. 30, no. 1, pp.239-249.
https://search.emarefa.net/detail/BIM-887136
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fabrizi, Fabrizio…[et al.]. Hepatitis C virus-induced glomerular disease and posterior reversible encephalopathy syndrome after liver transplant : case report and literature review. Saudi Journal of Kidney Diseases and Transplantation Vol. 30, no. 1 (Jan. / Feb. 2019), pp.239-249.
https://search.emarefa.net/detail/BIM-887136
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fabrizi, Fabrizio& Paolucci, Aldo& Antonelli, Barbara& Cerutti, Roberta& Donato, Francesca Maria& Lampertico, Pietro…[et al.]. Hepatitis C virus-induced glomerular disease and posterior reversible encephalopathy syndrome after liver transplant : case report and literature review. Saudi Journal of Kidney Diseases and Transplantation. 2019. Vol. 30, no. 1, pp.239-249.
https://search.emarefa.net/detail/BIM-887136
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 246-249
رقم السجل
BIM-887136
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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