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Effect of sertraline and fluoxetine on some biochemical parameters and histological changes in male and female laboratory rats Rattus norvegicus
المؤلفون المشاركون
Husayn, Ali Mani
Madlul, Zaman Subhi
Faris, Sattar Abbud
المصدر
Journal of College of Education for Pure Sciences
العدد
المجلد 9، العدد 2 (30 يونيو/حزيران 2019)، ص ص. 42-57، 16ص.
الناشر
جامعة ذي قار كلية التربية للعلوم الصرفة
تاريخ النشر
2019-06-30
دولة النشر
العراق
عدد الصفحات
16
التخصصات الرئيسية
الموضوعات
الملخص EN
The current study was designed to determine the effect of sertraline and fluoxetine drugs on some biochemicals and histologicals change of male and female rats.
The animals were divided into five groups (each group consisting of 5 males and 5 females), the first group (control) was injected with the physiological solution Nacl 0.9%, second group was injected with10 mg / kg of Sertraline, third group was injected with 20 mg / kg of sertraline, fourth group was injected with 5 mg / kg of fluoxetine and fifth group was injected with10 mg / kg fluoxetine.
The results showed that a significant increase (P≤0.05) in the concentration of urea and creatinine (except for the second group of females) in all treated group compared with control.
In the liver enzymes, the results showed that a significant decrease in the concentrations of aspartate transaminase enzyme, Alanine transaminase and alkaline phosphatase in all treated groups compared with the control group(P≤0.05).
The kidney tissue showed histological changes such as infiltration of inflammatory cell, congestion, hemorrhage, renal glomerular distraction and loss, renal tubular hypertrophy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Husayn, Ali Mani& Faris, Sattar Abbud& Madlul, Zaman Subhi. 2019. Effect of sertraline and fluoxetine on some biochemical parameters and histological changes in male and female laboratory rats Rattus norvegicus. Journal of College of Education for Pure Sciences،Vol. 9, no. 2, pp.42-57.
https://search.emarefa.net/detail/BIM-891278
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Husayn, Ali Mani…[et al.]. Effect of sertraline and fluoxetine on some biochemical parameters and histological changes in male and female laboratory rats Rattus norvegicus. Journal of College of Education for Pure Sciences Vol. 9, no. 2 (Jun. 2019), pp.42-57.
https://search.emarefa.net/detail/BIM-891278
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Husayn, Ali Mani& Faris, Sattar Abbud& Madlul, Zaman Subhi. Effect of sertraline and fluoxetine on some biochemical parameters and histological changes in male and female laboratory rats Rattus norvegicus. Journal of College of Education for Pure Sciences. 2019. Vol. 9, no. 2, pp.42-57.
https://search.emarefa.net/detail/BIM-891278
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 55-57
رقم السجل
BIM-891278
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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