Neutrophil-lymphocyte ratio and the platelet parameters as biomarkers of atopic dermatitis severity in children
المؤلفون المشاركون
Erol, Meltem
Gayret, Ozlem Bostan
Nacaroglu, Hikmat Tekin
Sener, Ahmet
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 21، العدد 7 (31 يوليو/تموز 2019)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2019-07-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease with a specific immuneand inflammatory mechanism.
This study investigates inflammatory biomarkers and their correlation with disease severity.
Objectives: The aim of this study is to determine the relationship between platelet parameters [(mean platelet volume (MPV), platelet distribution width (PDW)], the neutrophil-lymphocyte ratio (NLR), the platelet-lymphocyte ratio (PLR), and AD severity in children.
Methods: In this retrospective study, we reviewed patients diagnosed with AD and a healthy control group at the department of pediatrics at Health Sciences in a university-affiliated hospital in Istanbul, Turkey, between January 2015 and December 2016.
The study included 79 children with AD and 75 healthy controls.
AD severity was graded using the Scoring Atopic Dermatitis (SCORAD) index.
Complete blood count was measured, and NLR and PLR were calculated.
NLR, PLR, MPV, PDW were compared between AD patients and healthy controls, and the correlations between these indexes and clinical characteristics were analyzed.
Results: No significant difference was observed between patients and controls for MPV, NLR, and PLR (P = 0.708, P = 0.340, P = 0.179, respectively).
In the AD group, PDW was lower than controls (17.391.45, 18.041.65, P = 0.006).
In the severe AD group, MPV was higher (7.621.81, 6.641.16, P = 0.035) and PDW was lower than in the mild AD group (16.521.49, 17.931.44, P = 0.0001).
Conclusions: Mean MPV and PDW levels are correlated with atopic dermatitis severity in children.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gayret, Ozlem Bostan& Nacaroglu, Hikmat Tekin& Erol, Meltem& Sener, Ahmet. 2019. Neutrophil-lymphocyte ratio and the platelet parameters as biomarkers of atopic dermatitis severity in children. Iranian Red Crescent Medical Journal،Vol. 21, no. 7, pp.1-6.
https://search.emarefa.net/detail/BIM-892349
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gayret, Ozlem Bostan…[et al.]. Neutrophil-lymphocyte ratio and the platelet parameters as biomarkers of atopic dermatitis severity in children. Iranian Red Crescent Medical Journal Vol. 21, no. 7 (Jul. 2019), pp.1-6.
https://search.emarefa.net/detail/BIM-892349
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gayret, Ozlem Bostan& Nacaroglu, Hikmat Tekin& Erol, Meltem& Sener, Ahmet. Neutrophil-lymphocyte ratio and the platelet parameters as biomarkers of atopic dermatitis severity in children. Iranian Red Crescent Medical Journal. 2019. Vol. 21, no. 7, pp.1-6.
https://search.emarefa.net/detail/BIM-892349
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Text in English ; abstracts in .
رقم السجل
BIM-892349
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر