Using of 2,7-dihydroxynaphthalene as a novel reagent in spectrophotometric assay of chloramphenicol

العناوين الأخرى

استخدام 2,7 ثنائي هيدروكسيل النفثالين بوصفه كاشف جديد للتقدير الطيفي للكلورامفينيكول

المؤلفون المشاركون

Jamal, Sudad R.
Uthman, Nabil S.

المصدر

Rafidain Journal of Science

الناشر

جامعة الموصل كلية العلوم

تاريخ النشر

2019-04-30

دولة النشر

العراق

عدد الصفحات

8

التخصصات الرئيسية

الكيمياء

الموضوعات

الملخص الإنجليزي

An indirect spectrophotometric method for the determination of chloramphenicol (CAP) has been suggested.

The method is based on the oxidative coupling reaction of reduced chloramphenicol (R-CAP) with 2,7- dihydroxynaphthalene (2,7-DHN) reagent in the presence of potassium dichromate as oxidizing agent to produce brown colored, stable and soluble product.

This product showed maximum absorption at 544 nm.

Beer’s law is obeyed over the range 0.5-7.5.μg.ml-1 of R – CAP and molar absorptivity of 1.069×105 l.mol-1.cm-1 and Sandell's sensitivity index of 0.0030 μg.cm-2, limit of detection (LOD), limit of quantitation (LOQ), relative error (RE%) and relative standard deviation (RSD%) have been estimated.

The method has been successfully applied to the determination of CAP in drug formulations.

نوع البيانات

أوراق مؤتمرات

رقم السجل

BIM-894929

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Jamal, Sudad R.& Uthman, Nabil S.. 2019-04-30. Using of 2,7-dihydroxynaphthalene as a novel reagent in spectrophotometric assay of chloramphenicol. Growing Chemistry Science and its Application (3 : 2019 : Banghazi, Libya). . Vol. 28, no. 2 (Special issue) (2019), pp.56-63.Mosul Iraq : University of Mosul College of Science.
https://search.emarefa.net/detail/BIM-894929

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Jamal, Sudad R.& Uthman, Nabil S.. Using of 2,7-dihydroxynaphthalene as a novel reagent in spectrophotometric assay of chloramphenicol. . Mosul Iraq : University of Mosul College of Science. 2019-04-30.
https://search.emarefa.net/detail/BIM-894929

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Jamal, Sudad R.& Uthman, Nabil S.. Using of 2,7-dihydroxynaphthalene as a novel reagent in spectrophotometric assay of chloramphenicol. . Growing Chemistry Science and its Application (3 : 2019 : Banghazi, Libya).
https://search.emarefa.net/detail/BIM-894929