Lupus nephritis : an experience of a tertiary care center in Nepal
المؤلفون المشاركون
Tripathi, Prashant Mani
Bartaula, Bijay
Subedi, Manish
Dakhal, Sushil
Mudbhari, Bandana
Sharma, Sanjib Kumar
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 30، العدد 2 (30 إبريل/نيسان 2019)، ص ص. 462-469، 8ص.
الناشر
تاريخ النشر
2019-04-30
دولة النشر
السعودية
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Lupus nephritis (LN) is one of the common complications of systemic lupus erythematosus (SLE).
Timely treatment will decrease progression to chronic kidney disease.
Treatment varies with different stages for which biopsy is needed.
Controversies still exist regarding its requirement in management.
This is a retrospective study from September 2014 to August 2016 in B.
P.
Koirala Institute of Health Sciences, Dharan, Nepal among all patients with SLE and undergone renal biopsy.
Of 92 patients, most were female 85 (92.4%) with a median age of 32 years.
In this study, 80.4% had some clinical symptomatology.
Of the clinical manifestations, 41.3% had polyarthritis, edema (20.7%), and malar rash (17.4%).
Anti-nuclear antibody was positive in 80.4% and ds DNA in 70.7%.
Renal biopsy showed more number of patients 27 (35%) had Stage IV LN, followed by Stage I, 19 (24%), and Stage II, 16 (20%) LN.
Median urinary protein in Class I was 1.05 g, Class II (0.63 g), Class III (1.5 g), Class IV (2.44 g), Class V (3.99 g), and Class VI (4.7 g).
Only Stage IV had Kappa of 0.269 (P = 0.003) showing agreement between proteinuria and histological staging which was statistically significant (P <0.005).
However, overall Kappa analysis showed none to fair strength of agreement for different stages of LN (−0.014–0.269) with proteinuria.
Kappa (k) analysis showed none to fair strength of agreement for different stages of LN and proteinuria.
Hence, only proteinuria is not sufficient to replace the need of renal biopsy in LN.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bartaula, Bijay& Subedi, Manish& Dakhal, Sushil& Mudbhari, Bandana& Tripathi, Prashant Mani& Sharma, Sanjib Kumar. 2019. Lupus nephritis : an experience of a tertiary care center in Nepal. Saudi Journal of Kidney Diseases and Transplantation،Vol. 30, no. 2, pp.462-469.
https://search.emarefa.net/detail/BIM-895404
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bartaula, Bijay…[et al.]. Lupus nephritis : an experience of a tertiary care center in Nepal. Saudi Journal of Kidney Diseases and Transplantation Vol. 30, no. 2 (Mar. / Apr. 2019), pp.462-469.
https://search.emarefa.net/detail/BIM-895404
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bartaula, Bijay& Subedi, Manish& Dakhal, Sushil& Mudbhari, Bandana& Tripathi, Prashant Mani& Sharma, Sanjib Kumar. Lupus nephritis : an experience of a tertiary care center in Nepal. Saudi Journal of Kidney Diseases and Transplantation. 2019. Vol. 30, no. 2, pp.462-469.
https://search.emarefa.net/detail/BIM-895404
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 467-469
رقم السجل
BIM-895404
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر