Serum organochlorine pesticides residues and risk of cancer : a case-control study
المؤلفون المشاركون
Amin, Muhammad
Yusuf, Mashitah M.
Tahir, Muhammad
Navid Ahmad
Ansari, Muhammad Javid
Anjum, Sayyid Ishtiyaq
Khan, Shahid Allah
Ata Allah, Muhammad
Shawkat, Suhayl
Buneri, Islam Dad
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 25، العدد 7 (30 نوفمبر/تشرين الثاني 2018)، ص ص. 1284-1290، 7ص.
الناشر
تاريخ النشر
2018-11-30
دولة النشر
السعودية
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Organochlorine pesticides (OCPs) are frequently used worldwide as insecticides, fungicides, herbicides and termiticides and have been associated with a variety of cancers in animal and human studies.
In the present study, we examined residues of fourteen OCPs in the serum samples of diagnosed cancer patients and healthy residents of Karachi, Pakistan.
A random collection of fasting blood samples was carried out from the donors with informed consent.
Serum was separated within 2 h of blood collection and was then subjected to extraction with organic solvents followed by purification with florisil column.
The final organic extract of each serum sample was processed with Gas Chromatograph coupled with Electron Capture Detector (GC-ECD).
OCPs were detected in 97.59% of the cancer cases and 93.75% of the healthy subjects.
Mean concentrations of total OCPs (ROCPs) was found elevated in the cancer group (0.606 mg/kg) compared with the control group (0.322 mg/kg).
Endosulfan was the highest prevalent OCP with a mean concentration of 0.214 mg/kg in the cancer group and 0.166 mg/kg in the control group.
The second most prevalent OCP was 4,4-DDE with a mean concentration of 0.131 mg/kg in the cancer group and 0.019 mg/kg in the control group.
Highest level of ROCPs was detected in the breast cancer cases (20.411 mg/kg) with a mean level of (2.041 mg/kg).
In light of the obtained results and available literature on the subject, it has been concluded that OCPs are positively associated with the risk of various cancers in humans
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ata Allah, Muhammad& Yusuf, Mashitah M.& Shawkat, Suhayl& Anjum, Sayyid Ishtiyaq& Ansari, Muhammad Javid& Buneri, Islam Dad…[et al.]. 2018. Serum organochlorine pesticides residues and risk of cancer : a case-control study. Saudi Journal of Biological Sciences،Vol. 25, no. 7, pp.1284-1290.
https://search.emarefa.net/detail/BIM-896315
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ata Allah, Muhammad…[et al.]. Serum organochlorine pesticides residues and risk of cancer : a case-control study. Saudi Journal of Biological Sciences Vol. 25, no. 7 (Nov. 2018), pp.1284-1290.
https://search.emarefa.net/detail/BIM-896315
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ata Allah, Muhammad& Yusuf, Mashitah M.& Shawkat, Suhayl& Anjum, Sayyid Ishtiyaq& Ansari, Muhammad Javid& Buneri, Islam Dad…[et al.]. Serum organochlorine pesticides residues and risk of cancer : a case-control study. Saudi Journal of Biological Sciences. 2018. Vol. 25, no. 7, pp.1284-1290.
https://search.emarefa.net/detail/BIM-896315
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 1289-1290
رقم السجل
BIM-896315
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر