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Predictors of coronary calcification in Indian hemodialysis patients
المؤلفون المشاركون
Jamale, Tukaram
Hase, Niwrutti K.
Jasani, Rachana
Dedhia, Paras
Bajpai, Divya
Kumar, Rajesh
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 29، العدد 4 (31 أغسطس/آب 2018)، ص ص. 822-827، 6ص.
الناشر
تاريخ النشر
2018-08-31
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Several biomolecules potentially serve as promoters or inhibitors of calcification in dialysis patients which include fetuin A, matrix gla protein, osteopontin, osteoprotegerin, etc.
The primary aim was to compare the biomarkers of coronary artery calcification (CAC) and to study its role as predictors of CAC in hemodialysis (HD) patients.
Of 126 patients undergoing chronic HD, 100 patients completed the study.
Blood samples were drawn for serum creatinine, electrolytes, calcium, phosphorus, Vitamin D3, parathyroid hormone (PTH), lipid profile, high sensitivity C-reactive protein, ferritin, fetuin A, and fibroblast growth factor-23 (FGF-23).
Noncontrast Computed Tomography scan of the coronary arteries was conducted on all participants.
Participants who were positive for CAC (P group) were compared with those negative for CAC (N group) using two sample t-test.
Multiple logistic regression analysis was conducted to determine the predictors of CAC.
The prevalence of vascular calcification (VC) was 60% with higher prevalence seen in males (71%), older age group, patients with dialysis vintage >5 years (27%), and diabetic population (62%).
Mean serum phosphorus was significantly higher (P <0.001) and fetuin A (P <0.001) was significantly lower in the P group.
Age (OR: 1.2, P = 0.004), serum phosphorus (OR: 1.8, P = 0.024), and fetuin A (OR: 0.0006, P = 0.001) were found as predictors of CAC.
CAC was more prevalent in males, patients with higher age group and in those with longer dialysis vintage and diabetic population.
Participants with CAC exhibited significantly high phosphorus and low fetuin A levels.
Age, phosphorus level, and fetuin A were found to be predictors of CAC in dialysis patients.
FGF-23 could not predict CAC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jasani, Rachana& Hase, Niwrutti K.& Kumar, Rajesh& Dedhia, Paras& Jamale, Tukaram& Bajpai, Divya. 2018. Predictors of coronary calcification in Indian hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation،Vol. 29, no. 4, pp.822-827.
https://search.emarefa.net/detail/BIM-896523
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jasani, Rachana…[et al.]. Predictors of coronary calcification in Indian hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation Vol. 29, no. 4 (Jul. / Aug. 2018), pp.822-827.
https://search.emarefa.net/detail/BIM-896523
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jasani, Rachana& Hase, Niwrutti K.& Kumar, Rajesh& Dedhia, Paras& Jamale, Tukaram& Bajpai, Divya. Predictors of coronary calcification in Indian hemodialysis patients. Saudi Journal of Kidney Diseases and Transplantation. 2018. Vol. 29, no. 4, pp.822-827.
https://search.emarefa.net/detail/BIM-896523
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 827
رقم السجل
BIM-896523
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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