Evaluation of cytological and genetic effects of Tribulus terrestris fruit aqueous extract on cultured human lymphocytes

المؤلفون المشاركون

al-Asuli, Sufyan Muhammad
Qari, Samir Hasan M.

المصدر

Saudi Journal of Biological Sciences

العدد

المجلد 26، العدد 1 (31 يناير/كانون الثاني 2019)، ص ص. 91-95، 5ص.

الناشر

الجمعية السعودية لعلوم الحياة

تاريخ النشر

2019-01-31

دولة النشر

السعودية

عدد الصفحات

5

التخصصات الرئيسية

الأحياء

الموضوعات

الملخص EN

The current study was carried out to evaluate the genotoxic aspects of the aqueous extracts of the Tribulus terrestris fruits by comet assay and cytogenetic procedures conditions on cultured human peripheral blood lymphocyte.

After the treatment of the lymphocytes with four concentrations of the aqueous fruit extract of T.

terrestris (10, 20, 40 and 80 mg/L) for 24 h it was noticed that, the presence of micronuclei and/or chromosomal aberration were monitored and a significant increase of comet cells at high concentration of T.

terrestris extract 80 mg/L.

Also, this study showed that the presence of micronuclei, chromosomal aberration as a chromosomal gap, fragmentation, stickiness and necrotic cells were appeared and increased with high concentrations of T.

terrestris fruits extract (40–80 mg/L).

On the other hand, no significant difference was observed with the low concentration of the extract (10–20 mg/L) as compared with control.

The current study refers to the ability of the extract of T.

terrestris fruits to do damage in the target DNA at the higher concentrations.

Thus, it could be considered that the aqueous extracts of the T.

terrestris fruits have genotoxic effect in the therapeutic protocols if it used in high doses.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Qari, Samir Hasan M.& al-Asuli, Sufyan Muhammad. 2019. Evaluation of cytological and genetic effects of Tribulus terrestris fruit aqueous extract on cultured human lymphocytes. Saudi Journal of Biological Sciences،Vol. 26, no. 1, pp.91-95.
https://search.emarefa.net/detail/BIM-896647

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Qari, Samir Hasan M.& al-Asuli, Sufyan Muhammad. Evaluation of cytological and genetic effects of Tribulus terrestris fruit aqueous extract on cultured human lymphocytes. Saudi Journal of Biological Sciences Vol. 26, no. 1 (Jan. 2019), pp.91-95.
https://search.emarefa.net/detail/BIM-896647

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Qari, Samir Hasan M.& al-Asuli, Sufyan Muhammad. Evaluation of cytological and genetic effects of Tribulus terrestris fruit aqueous extract on cultured human lymphocytes. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 1, pp.91-95.
https://search.emarefa.net/detail/BIM-896647

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 95

رقم السجل

BIM-896647