Evaluation of LL 37 lipoprotein as innate immunity marker among Sudanese patients cutaneous Leishmania
المؤلفون المشاركون
Bakr, Ayat H.
Abu Grun, E. A.
Abd Rabbih, Abd al-Karim A.
Muhammad, Umaymah A.
Mukhtar, M. A.
Mudawi, Jad Allah
المصدر
Sudan Journal of Medical Sciences
العدد
المجلد 14، العدد 3 (30 سبتمبر/أيلول 2019)، ص ص. 91-96، 6ص.
الناشر
جامعة أم درمان الإسلامية كلية الطب
تاريخ النشر
2019-09-30
دولة النشر
السودان
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background: The leishmaniasis is a group of diseases with a broad range of clinical manifestations caused by several species of parasites belonging to the genus Leishmania.
LL-37/hCAP18, the only cathelicidin in human, is expressed as an 18-kDa preproprotein.
The most prominent function of cathelicidin is their ability to inhibit propagation of a diverse range of microorganisms, which occurs at a micromolar range.
Objective: The study was aimed to evaluate the LL37 plasma level in Leishmania Sudanese patients.
Methods: In a case-control study, 300 subjects were enrolled (200 as case and 100 controls); 5 ml venous blood was collected in EDTA container, then plasma was obtained and stored frozen at –80°C.
LL 37 was estimated using competitive ELISA.
The data were analyzed using SPSS version 21.
Results: The results revealed that 115 (57%) of Leishimania patients were male and 85 (43%) were female.
Plasma LL 37 level was significantly increased in Leishmania patients (1.30 ± 0.71) compared to the control (0.21 ± 0.20) with (p-value 0.000).
Conclusion: Leishmania patients had higher levels of plasma LL37, suggesting effective antimicrobial immunity process enhancing healing of cutaneous leishmaniasis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bakr, Ayat H.& Abu Grun, E. A.& Abd Rabbih, Abd al-Karim A.& Muhammad, Umaymah A.& Mukhtar, M. A.& Mudawi, Jad Allah. 2019. Evaluation of LL 37 lipoprotein as innate immunity marker among Sudanese patients cutaneous Leishmania. Sudan Journal of Medical Sciences،Vol. 14, no. 3, pp.91-96.
https://search.emarefa.net/detail/BIM-898889
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bakr, Ayat H.…[et al.]. Evaluation of LL 37 lipoprotein as innate immunity marker among Sudanese patients cutaneous Leishmania. Sudan Journal of Medical Sciences Vol. 14, no. 3 (2019), pp.91-96.
https://search.emarefa.net/detail/BIM-898889
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bakr, Ayat H.& Abu Grun, E. A.& Abd Rabbih, Abd al-Karim A.& Muhammad, Umaymah A.& Mukhtar, M. A.& Mudawi, Jad Allah. Evaluation of LL 37 lipoprotein as innate immunity marker among Sudanese patients cutaneous Leishmania. Sudan Journal of Medical Sciences. 2019. Vol. 14, no. 3, pp.91-96.
https://search.emarefa.net/detail/BIM-898889
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 95-96
رقم السجل
BIM-898889
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر