Occurrence of hypothyroidism, diabetes mellitus, and celiac disease in emirate children with down’s syndrome
المؤلفون المشاركون
Abd al-Razzaq, Yusuf
al-Azzabi, Tariq I.
al-Hamid, Sania M.
Atiyyah, Salimah
Dib, Asma'a
Abu Rawi, al-Hadi H.
المصدر
العدد
المجلد 33، العدد 5 (30 سبتمبر/أيلول 2018)، ص ص. 387-392، 6ص.
الناشر
المجلس العماني للاختصاصات الطبية
تاريخ النشر
2018-09-30
دولة النشر
سلطنة عمان
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives: Autoimmune diseases are known to occur in people with Down’s syndrome (DS), especially celiac disease, type 1 diabetes mellitus (DM), and hypothyroidism.
Since there are common genetic risk factors involved in the occurrence of these autoimmune disorders, the risks would differ in different populations.
We sought to determine the prevalence of type 1 DM, celiac disease, and hypothyroidism in Emirati patients with DS in Abu Dhabi, UAE.
Methods: Ninety-two patients with DS were investigated for the presence of anti-thyroid antibodies, antithyroglobulin, and anti-thyroid peroxidase antibodies for hypothyroidism, anti-glutamic acid decarboxylase antibodies for type 1 DM, and anti-tissue transglutaminase immunoglobulin A antibodies for celiac disease.
Results: Karyotyping was performed on 89 patients.
Eighty-seven had nondisjunction of chromosome 21 (97.8%), one was a mosaic, and one had translocation.
Of the patients studied, 19.6% had hypothyroidism, 4.3% had type 1 DM, and 1.1% had celiac disease.
Out of the 92 patients studied, 66 (71.7%) did not have any autoimmune disease, 25 (27.2%) had one autoimmune disease, and one (1.1%) had two autoimmune diseases.
Conclusions: Celiac disease was the least prevalent autoimmune disease in patients with DS patients, while type 1 DM and hypothyroidism were both significantly associated with DS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abd al-Razzaq, Yusuf& al-Azzabi, Tariq I.& al-Hamid, Sania M.& Atiyyah, Salimah& Dib, Asma'a& Abu Rawi, al-Hadi H.. 2018. Occurrence of hypothyroidism, diabetes mellitus, and celiac disease in emirate children with down’s syndrome. Oman Medical Journal،Vol. 33, no. 5, pp.387-392.
https://search.emarefa.net/detail/BIM-902498
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abd al-Razzaq, Yusuf…[et al.]. Occurrence of hypothyroidism, diabetes mellitus, and celiac disease in emirate children with down’s syndrome. Oman Medical Journal Vol. 33, no. 5 (Sep. 2018), pp.387-392.
https://search.emarefa.net/detail/BIM-902498
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abd al-Razzaq, Yusuf& al-Azzabi, Tariq I.& al-Hamid, Sania M.& Atiyyah, Salimah& Dib, Asma'a& Abu Rawi, al-Hadi H.. Occurrence of hypothyroidism, diabetes mellitus, and celiac disease in emirate children with down’s syndrome. Oman Medical Journal. 2018. Vol. 33, no. 5, pp.387-392.
https://search.emarefa.net/detail/BIM-902498
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 391-392
رقم السجل
BIM-902498
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر