![](/images/graphics-bg.png)
Chronic sleepdeprivation effects on ischemia-reperfusion injury : role of the sympathetic nervous syste
المؤلفون المشاركون
Askari, Sahar
Shubani, Samirah
Faqihi, Mahdih
Imani, Ali Rida
Edalatyzadel, Zahrah
Parsa, Huda
Sadeghniyat, Khosro
المصدر
العدد
المجلد 66، العدد 3 (30 سبتمبر/أيلول 2018)، ص ص. 139-143، 5ص.
الناشر
تاريخ النشر
2018-09-30
دولة النشر
لبنان
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objective: Chronic sleep deprivation has disturbing effects on health.The aim of this study is to assess the effects of chronic sleep deprivation on myocardial ischemiareperfusion injury.
Methods:Male Wistar rats were randomly divided into four groups;the heart of all the animals was perfused in the Langendorff apparatus using Krebs-Henseleit buffer.
Hearts were allowed a 15-minute recovery which was considered as baseline, then underwent 30 minutes ischemia followed by 60 minutes reperfusion.
Grouping: 1) Ischemia/ reperfusion group (IR); 2) Control group (CON): rats were placed in large multiple platforms for 72 hours prior to IR; 3) Chronic sleep deprivation group (CSD): 72 hours sleep deprivation was induced using small multiple platforms prior to IR;4) Sympathectomy group (SYMP):chemical sympathectomy was done 24 hours before chronic sleep deprivation induction followed by subjection to IR.
Outcome measures included heart rate (HR), left ventricular developed pressure (LVDP), rate product pressure (RPP) and the ratio of infarct size to area at risk (IS/AAR %).
Results:Our results showed IS/AAR considerably increased in the IR group as compared to the sleep deprivation group ( p < 0.001); and sympathectomy could decrease infarct size as compared to sleep deprivation ( p < 0.001).
There were no significant differences between HR, LVDP and RPP between groups.
Conclusions: Induction of 72 h sleep deprivation following ischemia and reperfusion increased the infarct size in a sympathetic dependent manner, and this effect of sleep deprivation is not related to changes in hemodynamic parameters.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shubani, Samirah& Faqihi, Mahdih& Imani, Ali Rida& Edalatyzadel, Zahrah& Askari, Sahar& Parsa, Huda…[et al.]. 2018. Chronic sleepdeprivation effects on ischemia-reperfusion injury : role of the sympathetic nervous syste. Journal Médical Libanais،Vol. 66, no. 3, pp.139-143.
https://search.emarefa.net/detail/BIM-904141
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shubani, Samirah…[et al.]. Chronic sleepdeprivation effects on ischemia-reperfusion injury : role of the sympathetic nervous syste. Journal Médical Libanais Vol. 66, no. 3 (2018), pp.139-143.
https://search.emarefa.net/detail/BIM-904141
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shubani, Samirah& Faqihi, Mahdih& Imani, Ali Rida& Edalatyzadel, Zahrah& Askari, Sahar& Parsa, Huda…[et al.]. Chronic sleepdeprivation effects on ischemia-reperfusion injury : role of the sympathetic nervous syste. Journal Médical Libanais. 2018. Vol. 66, no. 3, pp.139-143.
https://search.emarefa.net/detail/BIM-904141
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Text in English ; abstracts in French.
رقم السجل
BIM-904141
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)