![](/images/graphics-bg.png)
A comparative study of the effect of oral dextromethorphan and placebo on the pain after vitrectomy surgery : a double-blind, placebo-controlled, randomized clinical trial
المؤلفون المشاركون
Nikoubakht, Nasim
Sayarifard, Azadeh
Fayiz, Sayyid Hamid Rida
Rahimzadeh, Poupak
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 20، العدد 12 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2018-12-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background: Postoperative pain is a major complication in patients undergoing eye surgery.
N-methyl-D-aspartate (NMDA) receptor antagonists are widely used to manage postoperative pains.
Dextromethorphan, as an NMDA antagonist, is commonly used as an oral drug.
Objectives: This study was conducted to evaluate the effect of Dextromethorphan on post-operation pain and sedative effect in comparison to placebo.
Methods: A double-blinded, placebo-controlled, randomized clinical trial, upon 60 patients undergoing vitrectomy surgery was done.
Thirty patients received 30 mg oral Dextromethorphan before the operation, and 30 patients received a placebo.
Postoperation pain and sedation were evaluated after zero, one, two, and six hours.
Results: Post-operation pain was significantly lower in patients who received Dextromethorphan at zero, one, and two hours after operation (P < 0.001); however, not at six hours after operation (P = 0.11).
Sedative effect was higher in the Dextromethorphan group at zero (P = 0.03) and one hour (P = 0.01) after operation.
Conclusions: Prescribing oral Dextromethorphan before a vitrectomy surgery could reduce postoperative pain.
It also has postoperative sedation effects
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fayiz, Sayyid Hamid Rida& Nikoubakht, Nasim& Sayarifard, Azadeh& Rahimzadeh, Poupak. 2018. A comparative study of the effect of oral dextromethorphan and placebo on the pain after vitrectomy surgery : a double-blind, placebo-controlled, randomized clinical trial. Iranian Red Crescent Medical Journal،Vol. 20, no. 12, pp.1-6.
https://search.emarefa.net/detail/BIM-909115
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fayiz, Sayyid Hamid Rida…[et al.]. A comparative study of the effect of oral dextromethorphan and placebo on the pain after vitrectomy surgery : a double-blind, placebo-controlled, randomized clinical trial. Iranian Red Crescent Medical Journal Vol. 20, no. 12 (Dec. 2018), pp.1-6.
https://search.emarefa.net/detail/BIM-909115
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fayiz, Sayyid Hamid Rida& Nikoubakht, Nasim& Sayarifard, Azadeh& Rahimzadeh, Poupak. A comparative study of the effect of oral dextromethorphan and placebo on the pain after vitrectomy surgery : a double-blind, placebo-controlled, randomized clinical trial. Iranian Red Crescent Medical Journal. 2018. Vol. 20, no. 12, pp.1-6.
https://search.emarefa.net/detail/BIM-909115
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5-6
رقم السجل
BIM-909115
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)