A comparative study of the effect of oral dextromethorphan and placebo on the pain after vitrectomy surgery : a double-blind, placebo-controlled, randomized clinical trial
المؤلفون المشاركون
Nikoubakht, Nasim
Sayarifard, Azadeh
Fayiz, Sayyid Hamid Rida
Rahimzadeh, Poupak
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 20، العدد 12 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2018-12-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background: Postoperative pain is a major complication in patients undergoing eye surgery.
N-methyl-D-aspartate (NMDA) receptor antagonists are widely used to manage postoperative pains.
Dextromethorphan, as an NMDA antagonist, is commonly used as an oral drug.
Objectives: This study was conducted to evaluate the effect of Dextromethorphan on post-operation pain and sedative effect in comparison to placebo.
Methods: A double-blinded, placebo-controlled, randomized clinical trial, upon 60 patients undergoing vitrectomy surgery was done.
Thirty patients received 30 mg oral Dextromethorphan before the operation, and 30 patients received a placebo.
Postoperation pain and sedation were evaluated after zero, one, two, and six hours.
Results: Post-operation pain was significantly lower in patients who received Dextromethorphan at zero, one, and two hours after operation (P < 0.001); however, not at six hours after operation (P = 0.11).
Sedative effect was higher in the Dextromethorphan group at zero (P = 0.03) and one hour (P = 0.01) after operation.
Conclusions: Prescribing oral Dextromethorphan before a vitrectomy surgery could reduce postoperative pain.
It also has postoperative sedation effects
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fayiz, Sayyid Hamid Rida& Nikoubakht, Nasim& Sayarifard, Azadeh& Rahimzadeh, Poupak. 2018. A comparative study of the effect of oral dextromethorphan and placebo on the pain after vitrectomy surgery : a double-blind, placebo-controlled, randomized clinical trial. Iranian Red Crescent Medical Journal،Vol. 20, no. 12, pp.1-6.
https://search.emarefa.net/detail/BIM-909115
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fayiz, Sayyid Hamid Rida…[et al.]. A comparative study of the effect of oral dextromethorphan and placebo on the pain after vitrectomy surgery : a double-blind, placebo-controlled, randomized clinical trial. Iranian Red Crescent Medical Journal Vol. 20, no. 12 (Dec. 2018), pp.1-6.
https://search.emarefa.net/detail/BIM-909115
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fayiz, Sayyid Hamid Rida& Nikoubakht, Nasim& Sayarifard, Azadeh& Rahimzadeh, Poupak. A comparative study of the effect of oral dextromethorphan and placebo on the pain after vitrectomy surgery : a double-blind, placebo-controlled, randomized clinical trial. Iranian Red Crescent Medical Journal. 2018. Vol. 20, no. 12, pp.1-6.
https://search.emarefa.net/detail/BIM-909115
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5-6
رقم السجل
BIM-909115
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر