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cytomegalovirus end organ disease in Iranian HIV-1 infected patients with CD4+ cell counts less than 100 cellsmm3
المؤلفون المشاركون
Jabbari, Muhammad Rida
al-Sulaymaniyah, Huriyyah
Abd al-Baqi, Mahbubah Haji
al-Shirazi, Muhammad Sarraf
Malekshahi, Sumayyah Shatizadeh
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 21، العدد 11 (30 نوفمبر/تشرين الثاني 2019)5ص.
الناشر
تاريخ النشر
2019-11-30
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Background: Cytomegalovirus End-Organ Disease (CMV-EOD) is a seriously debilitating illness in patients with advanced HIV-1 infection, typically occurring with CD4+ cell counts of < 100 cells/mm3.
Objectives: This study aimed to evaluate the prevalence of CMV-EOD in adult patients with advanced HIV-1 infection (CD4+ count < 100 cells/mm3).
Methods: Using a convenience sampling method, a cross-sectional study was conducted on 82 patients with advanced HIV-1 infection in Iran between April 2016 and April 2018.
We collected baseline characteristics (age, sex, route of HIV-1 transmission, Hepatitis C Virus (HCV) infection, Hepatitis B Virus (HBV) infection, CMV IgG, and treatment status for HIV-1 infection) and CD4 counts.
The entire patients underwent clinical examinations for the diagnosis of CMV-EOD by experienced clinicians.
Statistical analysis was used to measure the differences between categorical variables and the outcome of CMV-EOD diagnosis.
Results: Fourteen (17.07%) out of 82 HIV-1-infected patients were diagnosed with opportunistic infection due to CMV.
Among 14 patients with CMV-EOD, retinitis occurred in the majority of patients (64.28%), followed by colitis (21.42%) and encephalitis (14.28%).
No significant correlation was found between the outcome of CMV-EOD and HBV infection (P = 1.00), HCV infection (P = 0.55), and treatment status for HIV-1 infection (P = 0.53).
We detected CMV-EOD more frequently among injecting drug users and patients with positive CMV-IgG (P = 0.12 and P = 0.41, respectively).
The ophthalmic examination had clinical usefulness for HIV-1 positive patients with CD4 counts of < 100/mm3.
Conclusions: It is assumed that the CD4+ cell count is not the sole predictor of the risk of developing CMV-EOD.
Further large-scale studies are required for a better understanding of risk factors involved in the occurrence of CMV-EOD in HIV-1 positive patients
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jabbari, Muhammad Rida& al-Sulaymaniyah, Huriyyah& Abd al-Baqi, Mahbubah Haji& al-Shirazi, Muhammad Sarraf& Malekshahi, Sumayyah Shatizadeh. 2019. cytomegalovirus end organ disease in Iranian HIV-1 infected patients with CD4+ cell counts less than 100 cellsmm3. Iranian Red Crescent Medical Journal،Vol. 21, no. 11.
https://search.emarefa.net/detail/BIM-910638
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jabbari, Muhammad Rida…[et al.]. cytomegalovirus end organ disease in Iranian HIV-1 infected patients with CD4+ cell counts less than 100 cellsmm3. Iranian Red Crescent Medical Journal Vol. 21, no. 11 (Nov. 2019).
https://search.emarefa.net/detail/BIM-910638
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jabbari, Muhammad Rida& al-Sulaymaniyah, Huriyyah& Abd al-Baqi, Mahbubah Haji& al-Shirazi, Muhammad Sarraf& Malekshahi, Sumayyah Shatizadeh. cytomegalovirus end organ disease in Iranian HIV-1 infected patients with CD4+ cell counts less than 100 cellsmm3. Iranian Red Crescent Medical Journal. 2019. Vol. 21, no. 11.
https://search.emarefa.net/detail/BIM-910638
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Text in English ; abstracts in .
رقم السجل
BIM-910638
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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