Estimation of MDA, CRP and some hematological parameters in the mature Cypriot thalassemia patients
المؤلفون المشاركون
Abd al-Jabbar, Ahmad Abd al-Jalal
Mehmetçik, Güldal
المصدر
ZANCO Journal of Pure and Applied Sciences
العدد
المجلد 31، العدد 4 (sup) (31 أغسطس/آب 2019)، ص ص. 143-149، 7ص.
الناشر
جامعة صلاح الدين قسم النشر العلمي
تاريخ النشر
2019-08-31
دولة النشر
العراق
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Thalassemia is a blood disorder has been known to passes down by parent to their offspring.
The root of this disorder mainly returns to the Mediterranean Countries.
Degradation of erythrocytes results in a thalassemia disease as a result of producing defeated Hemoglobin Molecules, due to changes occurring in their DNA structure like insertion or deletion.
For decades the only medical treatment those patients had is getting blood gave way by healthy volunteers.
As a result of this process, they receive lots of Iron minerals possibly causing oxidative Stress, Inflammation and splenomegaly.
The aim of the present work aimed to estimate the C-Reactive Proteins (CRP) as Biomarker of Inflammation, Serum Ferritin as Biomarker of Iron overload and MDA as A biomarker of oxidative Stress in patients B- thalassemia then comparing their data to healthy normal volunteers.
The study group consisted of 24 thalassemia patients and 24 control groups.
The blood samples of β-thalassemia cases were collected in thalassemia center In Dr.Burhan Nalbantoğlu Government Hospital/ Cyprus.
After centrifugation, Aliquots of serum and plasma has been stored for the later estimation CRP, MDA and serum ferritin.
Our data shows that the levels of C-reactive protein (1.350 ± 1.142 vs 0.325 ± 0.398; p<0.001), MDA (7.734 ± 1.557 vs 5.638 ± 1.219; p<0.001) and serum ferritin (617.92 ± 238.63 vs 433.82 ± 228.61; p=0.016) were significantly greater in contrast to same parameters of healthy controls.
overall, our study proved again that examining levels of CRP, MDA and serum ferritin could serve as good indicators of the risks possibly faces those patients, knowledge about the status of those parameters could offer Some Helpful Knowledge assisting health professionals in better management patients with β-Thalassemia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abd al-Jabbar, Ahmad Abd al-Jalal& Mehmetçik, Güldal. 2019. Estimation of MDA, CRP and some hematological parameters in the mature Cypriot thalassemia patients. ZANCO Journal of Pure and Applied Sciences،Vol. 31, no. 4 (sup), pp.143-149.
https://search.emarefa.net/detail/BIM-949183
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abd al-Jabbar, Ahmad Abd al-Jalal& Mehmetçik, Güldal. Estimation of MDA, CRP and some hematological parameters in the mature Cypriot thalassemia patients. ZANCO Journal of Pure and Applied Sciences Vol. 31, no. 4 (Supplement) (2019), pp.143-149.
https://search.emarefa.net/detail/BIM-949183
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abd al-Jabbar, Ahmad Abd al-Jalal& Mehmetçik, Güldal. Estimation of MDA, CRP and some hematological parameters in the mature Cypriot thalassemia patients. ZANCO Journal of Pure and Applied Sciences. 2019. Vol. 31, no. 4 (sup), pp.143-149.
https://search.emarefa.net/detail/BIM-949183
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 149
رقم السجل
BIM-949183
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر