Correlations between selenium levels and diabetes mellitus type 2 in chronic hepatitis c-infected patients
المؤلفون المشاركون
al-Khawajah, Salwa E.
Abd Allah, Isam M.
al-Shabrawi, Muhammad M.
Sulayman, Nashat M.
المصدر
Suez Canal University Medical Journal
العدد
المجلد 19، العدد 1 (30 يونيو/حزيران 2016)، ص ص. 48-59، 12ص.
الناشر
تاريخ النشر
2016-06-30
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Background : Plasma selenium (Se) concentrations corresponding to optimal health are highly dynamic and based on a combination of factors that need to be considered when assessing epidemiological data, such as the findings linking serum Se and type 2 diabetes mellitus (DM).
High serum Se concentrations may be associated with a higher occurrence of diabetes.
Aim: To evaluate the correlations between serum Se levels and DM in pa-tients with chronic Hepatitis C (CHC).
Patients and Methods : This case-control study in-cluded three groups; group 1 (29 CHC patients with DM), group 2 (29 CHC patients with-out DM) and group 3 (29 healthy control).
Subjects were tested for biochemical liver function tests, fasting blood sugar [FBS], and fasting insulin levels).
Homeostasis model assessment (HOMA)-insulin resistance (IR) was calculated.
Se levels were measured us-ing Atomic Absorption Spectroscopy.
Results: serum Se were significantly higher in group 1 and group 3 compared to group 2 (p < 0.01).
Meanwhile, serum Se were insignifi-cantly higher in group 1 than in group 3 (p > 0.05).
Cutoff value to differentiate diabetic and non-diabetic CHC patients using serum Se was >10 μg/l with sensitivity (76 %) and, specificity (86.2 %).
The incidence and the risk of Se deficiency were significantly higher among group 2 than among group 2 (24.1% vs.
3.4 %, respectively) (p < 0.05).
In entire CHC patients (group 1+group 2), the mean HOMA-IR values were significantly lower in the group with deficient Se levels than in the group with normal Se levels (p = 0.005).
A nega-tive correlations between serum Se levels and ALT levels, AST levels, and diabetes treat-ment was found.
Conclusions : Serum Se levels were significantly higher in CHC + DM group and in control group than in CHC group.
The incidence and the risk of Se deficiency were higher among HCV group compared to CHC + DM group.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sulayman, Nashat M.& al-Khawajah, Salwa E.& Abd Allah, Isam M.& al-Shabrawi, Muhammad M.. 2016. Correlations between selenium levels and diabetes mellitus type 2 in chronic hepatitis c-infected patients. Suez Canal University Medical Journal،Vol. 19, no. 1, pp.48-59.
https://search.emarefa.net/detail/BIM-959126
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sulayman, Nashat M.…[et al.]. Correlations between selenium levels and diabetes mellitus type 2 in chronic hepatitis c-infected patients. Suez Canal University Medical Journal Vol. 19, no. 1 (2016), pp.48-59.
https://search.emarefa.net/detail/BIM-959126
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sulayman, Nashat M.& al-Khawajah, Salwa E.& Abd Allah, Isam M.& al-Shabrawi, Muhammad M.. Correlations between selenium levels and diabetes mellitus type 2 in chronic hepatitis c-infected patients. Suez Canal University Medical Journal. 2016. Vol. 19, no. 1, pp.48-59.
https://search.emarefa.net/detail/BIM-959126
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 57-59
رقم السجل
BIM-959126
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر