Predictors of induction and sustainability of response to diuretic therapy in patients with decompensated chronic liver disease
المؤلفون المشاركون
Hasan, Muhammad F.
al-Shaturi, Muhammad A.
Ali, Hana E.
Khidr, Muhammad Salah al-Din
المصدر
Suez Canal University Medical Journal
العدد
المجلد 21، العدد 1 (30 يونيو/حزيران 2018)، ص ص. 18-23، 6ص.
الناشر
تاريخ النشر
2018-06-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background: Factors involved in individual’s response to loop diuretics in cirrhotic patients with ascites are many, which renders it difficult to austerely predict response to diuretic therapy in those patients.
The aim of this study was to evaluate factors which determine initial response to loop diuretic therapy in those patients and to determine whether such factors can predict a sustained diuresis response.
Patients and Methods: One hundred and ten patients with non-malignant chronic liver disease and ascites were treated with IV furosemide in doses according to serum creatinine together with oral spironolactone 50mg twice daily.
Before and during the diuretic therapy a set of clinical and laboratory variables were investigated as possible predictive factors influencing the therapeutic response to diuretics.
The renal arterial resistive index (RI) (reflecting renal vascular resistance) was estimated with duplex Doppler ultrasonography.
Results: Our study revealed statistically significant relation between high ascites grade(p=0.013), higher Child-Pugh class (p< 0.001), higher baseline serum creatinine & lower eGFR (p< 0.001), and high renal resistive index (p=0.002) with poor diuretic response.
Conclusion: combining both clinical and laboratory findings together with elevated baseline renal resistive index would be helpful in early identification of the subgroup of patients who are at higher risk of diuretic resistance.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Khidr, Muhammad Salah al-Din& Hasan, Muhammad F.& al-Shaturi, Muhammad A.& Ali, Hana E.. 2018. Predictors of induction and sustainability of response to diuretic therapy in patients with decompensated chronic liver disease. Suez Canal University Medical Journal،Vol. 21, no. 1, pp.18-23.
https://search.emarefa.net/detail/BIM-963674
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Khidr, Muhammad Salah al-Din…[et al.]. Predictors of induction and sustainability of response to diuretic therapy in patients with decompensated chronic liver disease. Suez Canal University Medical Journal Vol. 21, no. 1 (2018), pp.18-23.
https://search.emarefa.net/detail/BIM-963674
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Khidr, Muhammad Salah al-Din& Hasan, Muhammad F.& al-Shaturi, Muhammad A.& Ali, Hana E.. Predictors of induction and sustainability of response to diuretic therapy in patients with decompensated chronic liver disease. Suez Canal University Medical Journal. 2018. Vol. 21, no. 1, pp.18-23.
https://search.emarefa.net/detail/BIM-963674
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 23
رقم السجل
BIM-963674
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر