Anaplasma phagocytophilum and Anaplasma marginale Elicit Different Gene Expression Responses in Cultured Tick Cells

المؤلفون المشاركون

Kocan, Katherine M.
Naranjo, Victoria
Massung, Robert F.
Manzano-Roman, Raúl
de la Fuente, José
Blouin, Edmour F.
Jongejan, Frans
Almazán, Consuelo
Zivkovic, Zorica

المصدر

International Journal of Genomics

العدد

المجلد 2009، العدد 2009 (31 ديسمبر/كانون الأول 2009)، ص ص. 1-9، 9ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2009-06-28

دولة النشر

مصر

عدد الصفحات

9

التخصصات الرئيسية

الأحياء

الملخص EN

The genus Anaplasma (Rickettsiales: Anaplasmataceae) includes obligate tick-transmitted intracellular organisms, Anaplasma phagocytophilum and Anaplasma marginale that multiply in both vertebrate and tick host cells.

Recently, we showed that A.

marginale affects the expression of tick genes that are involved in tick survival and pathogen infection and multiplication.

However, the gene expression profile in A.

phagocytophilum-infected tick cells is currently poorly characterized.

The objectives of this study were to characterize tick gene expression profile in Ixodes scapularis ticks and cultured ISE6 cells in response to infection with A.

phagocypthilum and to compare tick gene expression responses in A.

phagocytophilum- and A.

marginale-infected tick cells by microarray and real-time RT-PCR analyses.

The results of these studies demonstrated modulation of tick gene expression by A.

phagocytophilum and provided evidence of different gene expression responses in tick cells infected with A.

phagocytophilum and A.

marginale.

These differences in Anaplasma-tick interactions may reflect differences in pathogen life cycle in the tick cells.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Zivkovic, Zorica& Blouin, Edmour F.& Manzano-Roman, Raúl& Almazán, Consuelo& Naranjo, Victoria& Massung, Robert F.…[et al.]. 2009. Anaplasma phagocytophilum and Anaplasma marginale Elicit Different Gene Expression Responses in Cultured Tick Cells. International Journal of Genomics،Vol. 2009, no. 2009, pp.1-9.
https://search.emarefa.net/detail/BIM-988529

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Zivkovic, Zorica…[et al.]. Anaplasma phagocytophilum and Anaplasma marginale Elicit Different Gene Expression Responses in Cultured Tick Cells. International Journal of Genomics No. 2009 (2009), pp.1-9.
https://search.emarefa.net/detail/BIM-988529

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Zivkovic, Zorica& Blouin, Edmour F.& Manzano-Roman, Raúl& Almazán, Consuelo& Naranjo, Victoria& Massung, Robert F.…[et al.]. Anaplasma phagocytophilum and Anaplasma marginale Elicit Different Gene Expression Responses in Cultured Tick Cells. International Journal of Genomics. 2009. Vol. 2009, no. 2009, pp.1-9.
https://search.emarefa.net/detail/BIM-988529

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-988529