Antihypertriglyceridemia and Anti-Inflammatory Activities of Monascus-Fermented Dioscorea in Streptozotocin-Induced Diabetic Rats
المؤلفون المشاركون
Liao, Jiunn-Wang
Shi, Yeu-Ching
Pan, Tzu-Ming
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-04-19
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
The rice fermented by Monascus, called red mold rice (RMR), and has a long tradition in East Asia as a dietary staple.
Monascus-fermented dioscorea called red mold dioscorea (RMD) contains various metabolites to perform the ability of reducing oxidative stress and anti-inflammatory response.
We used Wistar rats and induced diabetes by injecting streptozotocin (STZ, 65 mg/kg i.p.).
RMD was administered daily starting six weeks after disease onset.
Throughout the experimental period, significantly (P<.05) lowered plasma glucose, triglyceride, cholesterol, free fatty acid and low density lipoprotein levels were observed in the RMD-treated groups.
The RMD-treated diabetic rats showed higher activities of glutathione disulfide reductase, glutathione reductase, catalase and superoxide dismutase (P<.05) in the pancreas compared with the diabetic control rats.
RMD also inhibited diabetes-induced elevation in the levels of interleukin (IL)-1β, IL-6, interferon-γ and tumor necrosis factor-α.
Pancreatic β-cells damaged by STZ in the RMD supplemented groups were ameliorated.
The results of this study clearly demonstrated that RMD possesses several treatment-oriented properties, including the control of hyperglycemia, antioxidant effects, pancreatic β-cell protection and anti-inflammatory effects.
Considering these observations, it appears that RMD may be a useful supplement to delay the development of diabetes and its complications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shi, Yeu-Ching& Liao, Jiunn-Wang& Pan, Tzu-Ming. 2011. Antihypertriglyceridemia and Anti-Inflammatory Activities of Monascus-Fermented Dioscorea in Streptozotocin-Induced Diabetic Rats. Journal of Diabetes Research،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-990681
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shi, Yeu-Ching…[et al.]. Antihypertriglyceridemia and Anti-Inflammatory Activities of Monascus-Fermented Dioscorea in Streptozotocin-Induced Diabetic Rats. Journal of Diabetes Research No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-990681
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shi, Yeu-Ching& Liao, Jiunn-Wang& Pan, Tzu-Ming. Antihypertriglyceridemia and Anti-Inflammatory Activities of Monascus-Fermented Dioscorea in Streptozotocin-Induced Diabetic Rats. Journal of Diabetes Research. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-990681
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-990681
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر