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Chloroform Extract of Rasagenthi Mezhugu, a Siddha Formulation, as an Evidence-Based Complementary and Alternative Medicine for HPV-Positive Cervical Cancers
المؤلفون المشاركون
Riyasdeen, Anvarbatcha
Periasamy, Vaiyapuri S.
Paul, Preethy
Alshatwi, Ali A.
Akbarsha, Mohammad A.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-10-27
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Rasagenthi Mezhugu (RGM) is a herbomineral formulation in the Siddha system of traditional medicine and is prescribed in the southern parts of India as a remedy for all kinds of cancers.
However, scientific evidence for its therapeutic efficacy in cervical cancer is lacking, and it contains heavy metals.
To overcome these limitations, RGM was extracted, and the fractions were tested on HPV-positive cervical cancer cells, ME-180 and SiHa.
The extracts, free from the toxic heavy metals, affected the viability of both the cells.
The chloroform fraction (cRGM) induced DNA damage and apoptosis.
Mitochondria-mediated apoptosis was indicated.
Though both the cells responded to the treatment, ME-180 was more responsive.
Thus, this study brings up scientific evidence for the efficacy of RGM against the HPV-mediated cervical cancer cells and, if the toxic heavy metals are the limitation in its use, cRGM would be a suitable candidate as evidence-based complementary and alternative medicine for HPV-positive cervical cancers.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Riyasdeen, Anvarbatcha& Periasamy, Vaiyapuri S.& Paul, Preethy& Alshatwi, Ali A.& Akbarsha, Mohammad A.. 2011. Chloroform Extract of Rasagenthi Mezhugu, a Siddha Formulation, as an Evidence-Based Complementary and Alternative Medicine for HPV-Positive Cervical Cancers. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-992026
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Riyasdeen, Anvarbatcha…[et al.]. Chloroform Extract of Rasagenthi Mezhugu, a Siddha Formulation, as an Evidence-Based Complementary and Alternative Medicine for HPV-Positive Cervical Cancers. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-992026
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Riyasdeen, Anvarbatcha& Periasamy, Vaiyapuri S.& Paul, Preethy& Alshatwi, Ali A.& Akbarsha, Mohammad A.. Chloroform Extract of Rasagenthi Mezhugu, a Siddha Formulation, as an Evidence-Based Complementary and Alternative Medicine for HPV-Positive Cervical Cancers. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-992026
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-992026
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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