Hepatoprotective Activity of Elephantopus scaber on Alcohol-Induced Liver Damage in Mice
المؤلفون المشاركون
Alitheen, Noorjahan Banu Mohamed
Ho, Chai Ling
Ho, Wan Yong
Abdul Rahim, Raha
Yeap, Swee Keong
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-08-29
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Elephantopus scaber has been traditionally used as liver tonic.
However, the protective effect of E.
scaber on ethanol-induced liver damage is still unclear.
In this study, we have compared the in vivo hepatoprotective effect of E.
scaber with Phyllanthus niruri on the ethanol-induced liver damage in mice.
The total phenolic and total flavanoid content of E.
scaber ethanol extract were determined in this study.
Accelerating serum biochemical profiles (including AST, ALT, ALP, triglyceride, and total bilirubin) associated with fat drop and necrotic body in the liver section were observed in the mice treated with ethanol.
Low concentration of E.
scaber was able to reduce serum biochemical profiles and the fat accumulation in the liver.
Furthermore, high concentration of E.
scaber and positive control P.
niruri were able to revert the liver damage, which is comparable to the normal control.
Added to this, E.
scaber did not possess any oral acute toxicity on mice.
These results suggest the potential effect of this extract as a hepatoprotective agent towards-ethanol induced liver damage without any oral acute toxicity effect.
These activities might be contributed, or at least in part, by its high total phenolic and flavonoid contents.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ho, Wan Yong& Yeap, Swee Keong& Ho, Chai Ling& Abdul Rahim, Raha& Alitheen, Noorjahan Banu Mohamed. 2012. Hepatoprotective Activity of Elephantopus scaber on Alcohol-Induced Liver Damage in Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-992266
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ho, Wan Yong…[et al.]. Hepatoprotective Activity of Elephantopus scaber on Alcohol-Induced Liver Damage in Mice. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-992266
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ho, Wan Yong& Yeap, Swee Keong& Ho, Chai Ling& Abdul Rahim, Raha& Alitheen, Noorjahan Banu Mohamed. Hepatoprotective Activity of Elephantopus scaber on Alcohol-Induced Liver Damage in Mice. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-992266
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-992266
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر