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Cardioprotective Effect of the Compound Yangshen Granule in Rat Models with Acute Myocardial Infarction
المؤلفون المشاركون
Ming, Xie
Tongshen, Wang
Delin, Wu
Ronghua, Zhao
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-03-15
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The protective effect of Compound Yangshen Granules was observed in myocardial infarction rat model.
Rats were randomly divided into 6 groups: the model group, the control group (sham operated), the positive drug group, and small, medium, and large dosage of the Yangshen granule groups, respectively.
The rats in the 3 Yangshen granule groups were orally administrated with 0.7 g/kg, 1.4 g/kg, and 2.8 g/kg for 7 consecutive days, whereas the rats of the positive drug group treated with 0.14 g/kg of Danshen Dropping Pills, and rats in the control and model groups orally administrated with saline.
The rat model of acute myocardial infarction was established with ligation of coronary artery.
Electrocardiograms at different time points, the blood rheology, myocardial enzymes, infarct size, and myocardial morphologic changes were measured.
The results demonstrated that the granules could improve blood rheology, decrease st-segment of electrocardiograms and the activities of LDH and CK in serum, reduce myocardial infarction size, and alleviate myocardial histopathologic changes.
In addition, the effect of the granules depended on the dose administrated orally.
The results suggest that the Yangshen granules could produce cardioprotection effect and have potential benefits in the prevention of ischemic heart disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ming, Xie& Tongshen, Wang& Delin, Wu& Ronghua, Zhao. 2012. Cardioprotective Effect of the Compound Yangshen Granule in Rat Models with Acute Myocardial Infarction. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-992578
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ming, Xie…[et al.]. Cardioprotective Effect of the Compound Yangshen Granule in Rat Models with Acute Myocardial Infarction. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-992578
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ming, Xie& Tongshen, Wang& Delin, Wu& Ronghua, Zhao. Cardioprotective Effect of the Compound Yangshen Granule in Rat Models with Acute Myocardial Infarction. Evidence-Based Complementary and Alternative Medicine. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-992578
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-992578
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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