Comparison of Effects of the Ethanolic Extracts of Brazilian Propolis on Human Leukemic Cells As Assessed with the MTT Assay

المؤلفون المشاركون

Franchi, Gilberto C.
Moraes, Cleber S.
Toreti, Viviane C.
Daugsch, Andreas
Nowill, Alexandre E.
Park, Yong Kun

المصدر

Evidence-Based Complementary and Alternative Medicine

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2011-09-28

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الطب البشري

الملخص EN

Propolis is a resinous product collected by honey bees.

It was also reported that propolis has a wide variety of biological actions, including antimicrobial activity and antioxidant, anti-inflammatory, and suppressive effects of dioxin toxicity activities.

The aim of this study was to compare the in vitro cytotoxic activities of green propolis (G12) and red propolis (G13) in human leukemia cells.

These cells were incubated with different concentrations of propolis and 48 hours after the IC50 was calculated for each cell.

The results showed that the red propolis has cytotoxic effect in vitro higher than green propolis.

Red propolis was showed to be cytostatic in K562 cells and caused the same amount of apoptosis as its control Gleevec.

In conclusion, these results showed that red propolis is more cytotoxic than the green propolis in a variety of human cell lines of leukemia.

Red propolis may contain drugs capable of inhibiting cancer cell growth.

Therefore, further isolation of respective chemical ingredients from the red propolis (G13) for identification of the activities is necessary.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Franchi, Gilberto C.& Moraes, Cleber S.& Toreti, Viviane C.& Daugsch, Andreas& Nowill, Alexandre E.& Park, Yong Kun. 2011. Comparison of Effects of the Ethanolic Extracts of Brazilian Propolis on Human Leukemic Cells As Assessed with the MTT Assay. Evidence-Based Complementary and Alternative Medicine،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-992770

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Franchi, Gilberto C.…[et al.]. Comparison of Effects of the Ethanolic Extracts of Brazilian Propolis on Human Leukemic Cells As Assessed with the MTT Assay. Evidence-Based Complementary and Alternative Medicine No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-992770

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Franchi, Gilberto C.& Moraes, Cleber S.& Toreti, Viviane C.& Daugsch, Andreas& Nowill, Alexandre E.& Park, Yong Kun. Comparison of Effects of the Ethanolic Extracts of Brazilian Propolis on Human Leukemic Cells As Assessed with the MTT Assay. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-992770

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-992770