Autoimmunity and Extrahepatic Manifestations in Treatment-Naïve Children with Chronic Hepatitis C Virus Infection
المؤلفون المشاركون
Azzari, Chiara
Resti, Massimo
Olivito, Biagio
Indolfi, Giuseppe
Bartolini, Elisa
المصدر
Journal of Immunology Research
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-05-08
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Hepatitis C virus (HCV) infection has been associated with autoimmunity and extrahepatic manifestations in adults.
Few data are available on these topics in children.
Nonorgan specific auto-antibodies development is part of the natural course of chronic hepatitis C in children.
Smooth muscle autoantibody is the most common autoantibody found, while liver-kidney microsomal type-1 antibody positivity is the most peculiar autoimmune feature of children with HCV infection.
The clinical significance of non-organ specific autoantibodies in the course of paediatric chronic hepatitis C is still debated.
Autoantibody positivity can be considered neutral for most patients, while it can be associated with negative connotations for others, especially those positive for liver-kidney microsomal type-1 autoantibody.
Subclinical hypothyroidism but not autoimmune thyroiditis has been demonstrated in HCV infection in children, while only few cases of HCV-associated membranoproliferative glomerulonephritis have been described.
Single reports are available in the literature reporting the anecdotal association between chronic hepatitis C and other extrahepatic manifestations such as myopathy and opsoclonus-myoclonus syndrome.
Despite the low incidence of extrahepatic manifestations of chronic hepatitis C in children, overall, available data suggest a careful monitoring.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Indolfi, Giuseppe& Bartolini, Elisa& Olivito, Biagio& Azzari, Chiara& Resti, Massimo. 2012. Autoimmunity and Extrahepatic Manifestations in Treatment-Naïve Children with Chronic Hepatitis C Virus Infection. Journal of Immunology Research،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-996825
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Indolfi, Giuseppe…[et al.]. Autoimmunity and Extrahepatic Manifestations in Treatment-Naïve Children with Chronic Hepatitis C Virus Infection. Journal of Immunology Research Vol. 2012, no. 2012 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-996825
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Indolfi, Giuseppe& Bartolini, Elisa& Olivito, Biagio& Azzari, Chiara& Resti, Massimo. Autoimmunity and Extrahepatic Manifestations in Treatment-Naïve Children with Chronic Hepatitis C Virus Infection. Journal of Immunology Research. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-996825
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-996825
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر