Preparation and Properties of Biphasic Calcium Phosphate Scaffolds Multiply Coated with HAPLLA Nanocomposites for Bone Tissue Engineering Applications

المؤلفون المشاركون

Nie, Lei
Suo, Jinping
Zou, Peng
Feng, Shuibin

المصدر

Journal of Nanomaterials

العدد

المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-11، 11ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2012-04-11

دولة النشر

مصر

عدد الصفحات

11

التخصصات الرئيسية

الكيمياء
هندسة مدنية

الملخص EN

A well-developed BCP scaffolds coated with multilayer of HA/PLLA nanocomposites with interconnectivity, high porosity, and moderate compressive strength as well as good biocompatibility were fabricated for bone tissue engineering.

After being multiply coated with HA/PLLA nanocomposites, the scaffolds maintained the BCP framework structure, and the porous network structure of scaffolds remained unchanged; however, the compressive strength was increased with the increase of coating layer number of HA/PLLA nanocomposites.

The prepared scaffolds showed lower variation of pH values in SBF solution, and an increase of coating layer number led to the decrease of the biodegradation rate at different days.

Moreover, the multilayer coating scaffolds had good cytocompatibility, showing no negative effects on cells growth and proliferation.

Furthermore, the bone-like apatite layer was built obviously in the interface of scaffold after 21 days after implantation in SD rat muscle.

In conclusion, the BCP scaffold coated with multilayer of HA/PLLA nanocomposites could be a candidate as an excellent substitute for damaged or defect bone in bone tissue engineering.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Nie, Lei& Suo, Jinping& Zou, Peng& Feng, Shuibin. 2012. Preparation and Properties of Biphasic Calcium Phosphate Scaffolds Multiply Coated with HAPLLA Nanocomposites for Bone Tissue Engineering Applications. Journal of Nanomaterials،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-997463

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Nie, Lei…[et al.]. Preparation and Properties of Biphasic Calcium Phosphate Scaffolds Multiply Coated with HAPLLA Nanocomposites for Bone Tissue Engineering Applications. Journal of Nanomaterials No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-997463

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Nie, Lei& Suo, Jinping& Zou, Peng& Feng, Shuibin. Preparation and Properties of Biphasic Calcium Phosphate Scaffolds Multiply Coated with HAPLLA Nanocomposites for Bone Tissue Engineering Applications. Journal of Nanomaterials. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-997463

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-997463