Detection for MECA gene in Egyptian clinical Staphylococcus aureus samples and study their genotoxic activity

العناوين الأخرى

الكشف عن جين ال MecA في عزلات البكتريا العنقودية المصرية و دراسة السمية الوراثية الخاصة بها

المؤلفون المشاركون

Ibrahim, Samir Abd al-Aziz
al-Atiq, Sawsan Yusuf
Abd al-Raziq, Ashraf Bakri
Hasan, Marwah

المصدر

Arab Universities Journal of Agricultural Sciences

الناشر

جامعة عين شمس كلية الزراعة

تاريخ النشر

2019-03-31

دولة النشر

مصر

عدد الصفحات

9

التخصصات الرئيسية

العلوم الزراعية

الموضوعات

الملخص الإنجليزي

Staphylococcus aureus isolates were isolated from fifty clinical samples collected from Ain Shams University Hospitals (March - July 2016) and identified using biochemical and microbiological tests.

PCR was performed using specific primers to determine the isolates of Methicillin - Resistant Staphylococcus aureus (MRSA) based on the presence of mecA gene.

Thirty-four isolates from total fifty isolates (68% ) were identified as MRSA isolates.

To study the genotoxicity for this isolates, forty-five mice were injected with these MRSA isolates and comet and micronuclei assays were performed on mice liver tissues and bone marrow respectively.

These assays revealed 24% - 22% DNA damage as an indicator for chromosomal breakage by comet and micronucleus assays respectively which indicate that infection with these isolates leads to mutations.

Studying these isolate furthermore will give an insight on how critical maintaining high standard hygiene in Egyptian hospitals and attention to infection control system can prevent occur of outbreaks

نوع البيانات

أوراق مؤتمرات

رقم السجل

BIM-999839

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Hasan, Marwah& Ibrahim, Samir Abd al-Aziz& Abd al-Raziq, Ashraf Bakri& al-Atiq, Sawsan Yusuf. 2019-03-31. Detection for MECA gene in Egyptian clinical Staphylococcus aureus samples and study their genotoxic activity. . Vol. 27, no. 1 (s) (2019), pp.529-537.Cairo Egypt : Ain Shams University Faculty of Agriculture.
https://search.emarefa.net/detail/BIM-999839

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Hasan, Marwah…[et al.]. Detection for MECA gene in Egyptian clinical Staphylococcus aureus samples and study their genotoxic activity. . Cairo Egypt : Ain Shams University Faculty of Agriculture. 2019-03-31.
https://search.emarefa.net/detail/BIM-999839

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Hasan, Marwah& Ibrahim, Samir Abd al-Aziz& Abd al-Raziq, Ashraf Bakri& al-Atiq, Sawsan Yusuf. Detection for MECA gene in Egyptian clinical Staphylococcus aureus samples and study their genotoxic activity. .
https://search.emarefa.net/detail/BIM-999839