Antioxidant and antiradical activity of green tea (Camellia sinensis)‎ aqueous extract and its capability to retardation of rats liver cirrhosis

Other Title(s)

النشاط المضاد للأكسدة و الشقوق الحرة للمستخلص المائي للشاي الأخضر و قدرته على تأخير تليف الكبد في الفئران

Joint Authors

Bakr, Sayyid Mahmud Abd al-Hamid
Kishk, Yasir Fikri Muhammad
Ali, Suad Ahmad
al-Nawawi, Muhammad Abd al-Raziq

Source

Arab Universities Journal of Agricultural Sciences

Issue

Vol. 26, Issue 2 D (31 Dec. 2018), pp.2419-2438, 20 p.

Publisher

Ain Shams University Faculty of Agriculture

Publication Date

2018-12-31

Country of Publication

Egypt

No. of Pages

20

Main Subjects

Botany

Topics

Abstract EN

The aim of the present study was to optimize the extraction conditions of green tea aqueous extract [green tea concentration (G) and extraction temperature (T)].

Response surface methodology was applied to determine the highest radical scavenging activity (RSA), Ferric reducing antioxidant power (FRAP) and reducing power (RP) of the prepared green tea extract.

Effect of green tea aqueous extract prepared using the optimal conditions on the liver cirrhosis retardation in rats was also investigated.

Two-factors central composite design was established to determine the effects of G or T and radical scavenging holding time as independent variables on RSA, FRAP and RP as dependent variables.

The optimum G, T and holding time with maximum RSA were 1.0 %, 88.7 °C for 25 min, with a predicted RSA of 81.3 % (r2=0.9115) compared to the BHT, which had a scavenging value of 87.4 % at concentration 150 ppm and holding time 30 min The same predicted concentration and temperature obtained with the highest FRAP and RP were 2.566 and 1.687 with r2 0.9780 and 0.9550, respectively.

The phenolic and flavonoid contents were 81.2 mg gallic acid equivalent and 33.5 mg quercetin equivalent per 100 ml green tea extract.

The extract prepared at optimal conditions was used for treatment of cirrhotic rats by CCl4.

Insignificant (P≥0.05) differences were observed between the green tea group and control group in obtained total protein or albumin values.

Total protein and albumin were dramatically decreased in the group treated by CCL4.

The same trend was observed with studying the transaminase enzymes.

Histopathological sections appeared the effect of green tea extract on the retardation of liver cirrhosis in rats.

American Psychological Association (APA)

Bakr, Sayyid Mahmud Abd al-Hamid& Kishk, Yasir Fikri Muhammad& Ali, Suad Ahmad& al-Nawawi, Muhammad Abd al-Raziq. 2018. Antioxidant and antiradical activity of green tea (Camellia sinensis) aqueous extract and its capability to retardation of rats liver cirrhosis. Arab Universities Journal of Agricultural Sciences،Vol. 26, no. 2 D, pp.2419-2438.
https://search.emarefa.net/detail/BIM-929470

Modern Language Association (MLA)

Ali, Suad Ahmad…[et al.]. Antioxidant and antiradical activity of green tea (Camellia sinensis) aqueous extract and its capability to retardation of rats liver cirrhosis. Arab Universities Journal of Agricultural Sciences Vol. 26, no. 2 D (2018), pp.2419-2438.
https://search.emarefa.net/detail/BIM-929470

American Medical Association (AMA)

Bakr, Sayyid Mahmud Abd al-Hamid& Kishk, Yasir Fikri Muhammad& Ali, Suad Ahmad& al-Nawawi, Muhammad Abd al-Raziq. Antioxidant and antiradical activity of green tea (Camellia sinensis) aqueous extract and its capability to retardation of rats liver cirrhosis. Arab Universities Journal of Agricultural Sciences. 2018. Vol. 26, no. 2 D, pp.2419-2438.
https://search.emarefa.net/detail/BIM-929470

Data Type

Journal Articles

Language

English

Notes

Record ID

BIM-929470