Update on Transanal NOTES for Rectal Cancer: Transitioning to Human Trials
Joint Authors
Telem, Dana A.
Berger, David L.
Bordeianou, Liliana G.
Rattner, David W.
Sylla, Patricia
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-20
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The feasibility of natural orifice translumenal endoscopic surgery (NOTES) resection for rectal cancer has been demonstrated in both survival swine and fresh human cadaveric models.
In preparation for transitioning to human application, our group has performed transanal NOTES rectal resection in a large series of human cadavers.
This experience both solidified the feasibility of resection and allowed optimization of technique prior to clinical application.
Improvement in specimen length and operative time was demonstrated with increased experience and newer platforms.
This extensive laboratory experience has paved the way for successful clinical translation resulting in an ongoing clinical trial.
To date, based on published reports, 4 human subjects have undergone successful hybrid transanal NOTES resection of rectal cancer.
While promising, instrument limitations continue to hinder a pure transanal approach.
Careful patient selection and continued development of new endoscopic and flexible-tip instruments are imperative prior to pure NOTES clinical application.
American Psychological Association (APA)
Telem, Dana A.& Berger, David L.& Bordeianou, Liliana G.& Rattner, David W.& Sylla, Patricia. 2012. Update on Transanal NOTES for Rectal Cancer: Transitioning to Human Trials. Minimally Invasive Surgery،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1001280
Modern Language Association (MLA)
Telem, Dana A.…[et al.]. Update on Transanal NOTES for Rectal Cancer: Transitioning to Human Trials. Minimally Invasive Surgery No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-1001280
American Medical Association (AMA)
Telem, Dana A.& Berger, David L.& Bordeianou, Liliana G.& Rattner, David W.& Sylla, Patricia. Update on Transanal NOTES for Rectal Cancer: Transitioning to Human Trials. Minimally Invasive Surgery. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-1001280
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1001280