The Predictive Value of Interim and Final [18F] Fluorodeoxyglucose Positron Emission Tomography after Rituximab-Chemotherapy in the Treatment of Non-Hodgkin's Lymphoma: A Meta-Analysis
Joint Authors
Zhu, Yuyuan
Lu, Jianda
Wei, Xin
Song, Shaoli
Huang, Gang
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background and Purpose.
The aim of this study is to determine the prognostic value of interim and final FDG-PET in major histotypes of B-cell NHL patients treated with rituximab containing-chemotherapy.
Methods.
We searched for articles published in English, limited to lymphoma, rituximab, and FDG-PET, and dedicated to deal with the impact on progression and survival.
The log hazard ratios (HR) and their variances were estimated.
Results.
A PubMed and Scopus review of published trials identified 13 studies of Progression-free survival (PFS) and overall survival (OS) which were set as the main outcome measures.
The combined HRs of I-PET for PFS and OS in DLBCL were 4.4 (P=0.11) and 3.99 (P=0.46), respectively.
The combined HRs of F-PET for PFS and OS in DLBCL were 5.91 (P=0.39) and 6.75 (P=0.92), respectively.
Regarding to non-DLBCL with F-PET, the combined HRs of F-PET for PFS and OS were 4.05 (P=0.79) and 5.1 (P=0.51), respectively.
No publication bias existed.
Conclusion.
In DLBCL, both I-PET and F-PET can be performed for survival and progression analysis.
But in other B-cell subtypes such as follicular lymphoma (FL) and mantle cell lymphoma (MCL), it would be necessary to perform F-PET for predictive purposes.
American Psychological Association (APA)
Zhu, Yuyuan& Lu, Jianda& Wei, Xin& Song, Shaoli& Huang, Gang. 2013. The Predictive Value of Interim and Final [18F] Fluorodeoxyglucose Positron Emission Tomography after Rituximab-Chemotherapy in the Treatment of Non-Hodgkin's Lymphoma: A Meta-Analysis. BioMed Research International،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1003860
Modern Language Association (MLA)
Zhu, Yuyuan…[et al.]. The Predictive Value of Interim and Final [18F] Fluorodeoxyglucose Positron Emission Tomography after Rituximab-Chemotherapy in the Treatment of Non-Hodgkin's Lymphoma: A Meta-Analysis. BioMed Research International No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1003860
American Medical Association (AMA)
Zhu, Yuyuan& Lu, Jianda& Wei, Xin& Song, Shaoli& Huang, Gang. The Predictive Value of Interim and Final [18F] Fluorodeoxyglucose Positron Emission Tomography after Rituximab-Chemotherapy in the Treatment of Non-Hodgkin's Lymphoma: A Meta-Analysis. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1003860
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1003860