Role of Intracellular Ca2+ and Na+Ca2+ Exchanger in the Pathogenesis of Contrast-Induced Acute Kidney Injury

Joint Authors

Yang, Dingping
Yang, Dingwei

Source

BioMed Research International

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-11-18

Country of Publication

Egypt

No. of Pages

5

Main Subjects

Medicine

Abstract EN

The precise mechanisms underlying contrast-induced acute kidney injury (CI-AKI) are not well understood.

Intracellular Ca2+ overload is considered to be a key factor in CI-AKI.

Voltage-dependent Ca2+ channel (VDC) and Na+/Ca2+ exchanger (NCX) system are the main pathways of intracellular Ca2+ overload in pathological conditions.

Here, we review the potential underlying mechanisms involved in CI-AKI and discuss the role of NCX-mediated intracellular Ca2+ overload in the contrast media-induced renal tubular cell injury and renal hemodynamic disorder.

American Psychological Association (APA)

Yang, Dingping& Yang, Dingwei. 2013. Role of Intracellular Ca2+ and Na+Ca2+ Exchanger in the Pathogenesis of Contrast-Induced Acute Kidney Injury. BioMed Research International،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1004833

Modern Language Association (MLA)

Yang, Dingping& Yang, Dingwei. Role of Intracellular Ca2+ and Na+Ca2+ Exchanger in the Pathogenesis of Contrast-Induced Acute Kidney Injury. BioMed Research International No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-1004833

American Medical Association (AMA)

Yang, Dingping& Yang, Dingwei. Role of Intracellular Ca2+ and Na+Ca2+ Exchanger in the Pathogenesis of Contrast-Induced Acute Kidney Injury. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1004833

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1004833