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Role of Intracellular Ca2+ and Na+Ca2+ Exchanger in the Pathogenesis of Contrast-Induced Acute Kidney Injury
Joint Authors
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The precise mechanisms underlying contrast-induced acute kidney injury (CI-AKI) are not well understood.
Intracellular Ca2+ overload is considered to be a key factor in CI-AKI.
Voltage-dependent Ca2+ channel (VDC) and Na+/Ca2+ exchanger (NCX) system are the main pathways of intracellular Ca2+ overload in pathological conditions.
Here, we review the potential underlying mechanisms involved in CI-AKI and discuss the role of NCX-mediated intracellular Ca2+ overload in the contrast media-induced renal tubular cell injury and renal hemodynamic disorder.
American Psychological Association (APA)
Yang, Dingping& Yang, Dingwei. 2013. Role of Intracellular Ca2+ and Na+Ca2+ Exchanger in the Pathogenesis of Contrast-Induced Acute Kidney Injury. BioMed Research International،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1004833
Modern Language Association (MLA)
Yang, Dingping& Yang, Dingwei. Role of Intracellular Ca2+ and Na+Ca2+ Exchanger in the Pathogenesis of Contrast-Induced Acute Kidney Injury. BioMed Research International No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-1004833
American Medical Association (AMA)
Yang, Dingping& Yang, Dingwei. Role of Intracellular Ca2+ and Na+Ca2+ Exchanger in the Pathogenesis of Contrast-Induced Acute Kidney Injury. BioMed Research International. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-1004833
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1004833