A Novel Framework Based on ACO and PSO for RNA Secondary Structure Prediction
Joint Authors
Wang, Gang
Zhang, Wen-yi
Ning, Qiao
Chen, Hui-ling
Source
Mathematical Problems in Engineering
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Prediction of RNA structure is a useful process for creating new drugs and understanding genetic diseases.
In this paper, we proposed a particle swarm optimization (PSO) and ant colony optimization (ACO) based framework (PAF) for RNA secondary structure prediction.
PAF consists of crucial stem searching (CSS) and global sequence building (GSB).
In CSS, a modified ACO (MACO) is used to search the crucial stems, and then a set of stems are generated.
In GSB, we used a modified PSO (MPSO) to construct all the stems in one sequence.
We evaluated the performance of PAF on ten sequences, which have length from 122 to 1494.
We also compared the performance of PAF with the results obtained from six existing well-known methods, SARNA-Predict, RnaPredict, ACRNA, PSOfold, IPSO, and mfold.
The comparison results show that PAF could not only predict structures with higher accuracy rate but also find crucial stems.
American Psychological Association (APA)
Wang, Gang& Zhang, Wen-yi& Ning, Qiao& Chen, Hui-ling. 2013. A Novel Framework Based on ACO and PSO for RNA Secondary Structure Prediction. Mathematical Problems in Engineering،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1010771
Modern Language Association (MLA)
Wang, Gang…[et al.]. A Novel Framework Based on ACO and PSO for RNA Secondary Structure Prediction. Mathematical Problems in Engineering No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-1010771
American Medical Association (AMA)
Wang, Gang& Zhang, Wen-yi& Ning, Qiao& Chen, Hui-ling. A Novel Framework Based on ACO and PSO for RNA Secondary Structure Prediction. Mathematical Problems in Engineering. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-1010771
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1010771