Molecular Docking Study of Conformational Polymorph: Building Block of Crystal Chemistry
Joint Authors
Dubey, Rashmi
Tewari, Ashish Kumar
Singh, Ved Prakash
Singh, Praveen
Dangi, Jawahar Singh
Puerta, Carmen
Valerga, Pedro
Kant, Rajni
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Two conformational polymorphs of novel 2-[2-(3-cyano-4,6-dimethyl-2-oxo-2H-pyridin-1-yl)-ethoxy]-4,6-dimethyl nicotinonitrile have been developed.
The crystal structure of both polymorphs (1a and 1b) seems to be stabilized by weak interactions.
A difference was observed in the packing of both polymorphs.
Polymorph 1b has a better binding affinity with the cyclooxygenase (COX-2) receptor than the standard (Nimesulide).
American Psychological Association (APA)
Dubey, Rashmi& Tewari, Ashish Kumar& Singh, Ved Prakash& Singh, Praveen& Dangi, Jawahar Singh& Puerta, Carmen…[et al.]. 2013. Molecular Docking Study of Conformational Polymorph: Building Block of Crystal Chemistry. The Scientific World Journal،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1011935
Modern Language Association (MLA)
Dubey, Rashmi…[et al.]. Molecular Docking Study of Conformational Polymorph: Building Block of Crystal Chemistry. The Scientific World Journal No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-1011935
American Medical Association (AMA)
Dubey, Rashmi& Tewari, Ashish Kumar& Singh, Ved Prakash& Singh, Praveen& Dangi, Jawahar Singh& Puerta, Carmen…[et al.]. Molecular Docking Study of Conformational Polymorph: Building Block of Crystal Chemistry. The Scientific World Journal. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-1011935
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1011935
