Four-Dimensional Computed Tomography Based Respiratory-Gated Radiotherapy with Respiratory Guidance System: Analysis of Respiratory Signals and Dosimetric Comparison
Joint Authors
Lee, Jung Ae
Kim, Chul Yong
Yang, Dae Sik
Yoon, Won Sup
Park, Young Je
Lee, Suk
Kim, Young Bum
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-07
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Purpose.
To investigate the effectiveness of respiratory guidance system in 4-dimensional computed tomography (4DCT) based respiratory-gated radiation therapy (RGRT) by comparing respiratory signals and dosimetric analysis of treatment plans.
Methods.
The respiratory amplitude and period of the free, the audio device-guided, and the complex system-guided breathing were evaluated in eleven patients with lung or liver cancers.
The dosimetric parameters were assessed by comparing free breathing CT plan and 4DCT-based 30–70% maximal intensity projection (MIP) plan.
Results.
The use of complex system-guided breathing showed significantly less variation in respiratory amplitude and period compared to the free or audio-guided breathing regarding the root mean square errors (RMSE) of full inspiration (P=0.031), full expiration (P=0.007), and period (P=0.007).
The dosimetric parameters including V5 Gy, V10 Gy, V20 Gy, V30 Gy, V40 Gy, and V50 Gy of normal liver or lung in 4DCT MIP plan were superior over free breathing CT plan.
Conclusions.
The reproducibility and regularity of respiratory amplitude and period were significantly improved with the complex system-guided breathing compared to the free or the audio-guided breathing.
In addition, the treatment plan based on the 4D CT-based MIP images acquired with the complex system guided breathing showed better normal tissue sparing than that on the free breathing CT.
American Psychological Association (APA)
Lee, Jung Ae& Kim, Chul Yong& Yang, Dae Sik& Yoon, Won Sup& Park, Young Je& Lee, Suk…[et al.]. 2014. Four-Dimensional Computed Tomography Based Respiratory-Gated Radiotherapy with Respiratory Guidance System: Analysis of Respiratory Signals and Dosimetric Comparison. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1016216
Modern Language Association (MLA)
Lee, Jung Ae…[et al.]. Four-Dimensional Computed Tomography Based Respiratory-Gated Radiotherapy with Respiratory Guidance System: Analysis of Respiratory Signals and Dosimetric Comparison. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1016216
American Medical Association (AMA)
Lee, Jung Ae& Kim, Chul Yong& Yang, Dae Sik& Yoon, Won Sup& Park, Young Je& Lee, Suk…[et al.]. Four-Dimensional Computed Tomography Based Respiratory-Gated Radiotherapy with Respiratory Guidance System: Analysis of Respiratory Signals and Dosimetric Comparison. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1016216
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1016216